TWIST1 Antikörper (AA 9-74)

Produktnummer ABIN1098133

Produktdetails anti-TWIST1 Antikörper

Target: TWIST1 (Twist Homolog 1 (Drosophila) (TWIST1))

Bindungsspezifität: AA 9-74

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser TWIST1 Antikörper ist unkonjugiert

Applikation: ELISA

Verwendungszweck: TWIST1 Antibody

Aufreinigung: Purified antibody

Immunogen: Purified recombinant fragment of human TWIST1 (AA: 9-74) expressed in E. Coli.

Klon: 2F8E7

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: ELISA: 1/10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Referenzen für anti-TWIST1 Antikörper (ABIN1098133)

Yu, Li, Lu, Tian, Ma, Wang, Xu: "Down-regulation of TWIST decreases migration and invasion of laryngeal carcinoma Hep-2 cells by regulating the E-cadherin, N-cadherin expression." in: Journal of cancer research and clinical oncology, Vol. 137, Issue 10, pp. 1487-93, (2011) (PubMed).

Casas, Kim, Bendesky, Ohno-Machado, Wolfe, Yang: "Snail2 is an essential mediator of Twist1-induced epithelial mesenchymal transition and metastasis." in: Cancer research, Vol. 71, Issue 1, pp. 245-54, (2011) (PubMed).

Details zu TWIST1

Target: TWIST1 (Twist Homolog 1 (Drosophila) (TWIST1))

Andere Bezeichnung: TWIST1 (TWIST1 Produkte)

Synonyme: scs antikoerper, Xtwi antikoerper, acs3 antikoerper, X-twi antikoerper, bpes2 antikoerper, bpes3 antikoerper, twist antikoerper, Xtwist antikoerper, MGC69439 antikoerper, twist1 antikoerper, ACS3 antikoerper, BPES2 antikoerper, BPES3 antikoerper, CRS1 antikoerper, SCS antikoerper, TWIST antikoerper, bHLHa38 antikoerper, AA960487 antikoerper, M-Twist antikoerper, Pde antikoerper, Ska10 antikoerper, Ska antikoerper, Twist antikoerper, pdt antikoerper, cTwist antikoerper, Twist1b antikoerper, twist-1 antikoerper, wu:fd04c01 antikoerper, zgc:101115 antikoerper, twist family bHLH transcription factor 1 antikoerper, twist family bHLH transcription factor 1 S homeolog antikoerper, twist basic helix-loop-helix transcription factor 1 antikoerper, twist homolog 1 (Drosophila) antikoerper, twist family bHLH transcription factor 1a antikoerper, TWIST1 antikoerper, twist1 antikoerper, twist1.S antikoerper, Twist1 antikoerper, twist1a antikoerper

Hintergrund:

Description: Basic helix-loop-helix (bHLH) transcription factors have been implicated in cell lineage determination and differentiation. The protein encoded by this gene is a bHLH transcription factor and shares similarity with another bHLH transcription factor, Dermo1. The strongest expression of this mRNA is in placental tissue, in adults, mesodermally derived tissues express this mRNA preferentially. Mutations in this gene have been found in patients with Saethre-Chotzen syndrome.

Aliases: SCS, ACS3, CRS1, BPES2, BPES3, TWIST, bHLHa38

Molekulargewicht: 21kDa

Gen-ID: 7291

HGNC: 7291

UniProt: Q15672

Pathways: p53 Signalweg, Proton Transport, Tube Formation, Negative Regulation of Transporter Activity