DKK3 Antikörper (AA 91-350)

Produktnummer ABIN1098142

Produktdetails anti-DKK3 Antikörper

Target: DKK3

Bindungsspezifität: AA 91-350

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser DKK3 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Verwendungszweck: DKK3 Antibody

Aufreinigung: Purified antibody

Immunogen: Purified recombinant fragment of human DKK3 (AA: 91-350 ) expressed in E. Coli.

Klon: 8A5C6

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1/10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Referenzen für anti-DKK3 Antikörper (ABIN1098142)

Du, Kataoka, Sakaguchi, Abarzua, Than, Sonegawa, Makino, Shimizu, Huh: "Expression of REIC/Dkk-3 in normal and hyperproliferative epidermis." in: Experimental dermatology, Vol. 20, Issue 3, pp. 273-7, (2011) (PubMed).

Medinger, Tzankov, Kern, Pircher, Hermann, Ott, Gastl, Untergasser, Gunsilius: "Increased Dkk3 protein expression in platelets and megakaryocytes of patients with myeloproliferative neoplasms." in: Thrombosis and haemostasis, Vol. 105, Issue 1, pp. 72-80, (2011) (PubMed).

Details zu DKK3

Target: DKK3

Abstract: DKK3 Produkte

Synonyme: REIC antikoerper, RIG antikoerper, reic antikoerper, dkk-3 antikoerper, AW061014 antikoerper, C87148 antikoerper, Reic antikoerper, p29 antikoerper, dickkopf WNT signaling pathway inhibitor 3 antikoerper, dickkopf WNT signaling pathway inhibitor 3 S homeolog antikoerper, DKK3 antikoerper, dkk3 antikoerper, dkk3.S antikoerper, Dkk3 antikoerper

Hintergrund:

Description: This gene encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. The expression of this gene is decreased in a variety of cancer cell lines and it may function as a tumor suppressor gene. Alternative splicing results in multiple transcript variants encoding the same protein.

Aliases: RIG, REIC

Molekulargewicht: 38.3kDa

Gen-ID: 27122

HGNC: 27122

UniProt: Q9UBP4