Mesp2 Antikörper (AA 37-94)

Produktnummer ABIN1098148

Produktdetails anti-Mesp2 Antikörper

Target: Mesp2 (Mesoderm Posterior 2 Homolog (Mesp2))

Bindungsspezifität: AA 37-94

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Mesp2 Antikörper ist unkonjugiert

Applikation: ELISA

Verwendungszweck: MESP2 Antibody

Aufreinigung: Purified antibody

Immunogen: Purified recombinant fragment of human MESP2 (AA: 37-94 ) expressed in E. Coli.

Klon: 1B3F9

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1/10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Referenzen für anti-Mesp2 Antikörper (ABIN1098148)

Qiu, Zhou, Jiang, Ji, Ding, Lv, Liu, Tang, Cheng, Qiu: "Mutation analysis of MESP2, HES7 and DUSP6 gene exons in patients with congenital scoliosis." in: Studies in health technology and informatics, Vol. 176, pp. 52-5, (2012) (PubMed).

Cornier, Staehling-Hampton, Delventhal, Saga, Caubet, Sasaki, Ellard, Young, Ramirez, Carlo, Torres, Emans, Turnpenny, Pourquié: "Mutations in the MESP2 gene cause spondylothoracic dysostosis/Jarcho-Levin syndrome." in: American journal of human genetics, Vol. 82, Issue 6, pp. 1334-41, (2008) (PubMed).

Details zu Mesp2

Target: Mesp2 (Mesoderm Posterior 2 Homolog (Mesp2))

Andere Bezeichnung: MESP2 (Mesp2 Produkte)

Synonyme: bHLHc6 antikoerper, SCDO2 antikoerper, mesoderm posterior 2 antikoerper, mesoderm posterior bHLH transcription factor 2 antikoerper, Mesp2 antikoerper, MESP2 antikoerper

Hintergrund:

Description: This gene encodes a member of the bHLH family of transcription factors and plays a key role in defining the rostrocaudal patterning of somites via interactions with multiple Notch signaling pathways. This gene is expressed in the anterior presomitic mesoderm and is downregulated immediately after the formation of segmented somites. This gene also plays a role in the formation of epithelial somitic mesoderm and cardiac mesoderm. Mutations in the MESP2 gene cause autosomal recessive spondylocostal dystosis 2 (SCD02).

Aliases: SCDO2, bHLHc6

Molekulargewicht: 41.8kDa

Gen-ID: 145873

HGNC: 145873

UniProt: Q0VG99