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Osteopontin Antikörper (AA 167-314)

Name: Osteopontin Antikörper (AA 167-314)
Brand: antibodies-online
SKU: ABIN1098149
Price: 614.71 EUR
Availability: InStock

SPP1 Reaktivität: Human ELISA, IHC, ICC Wirt: Maus Monoclonal 7C5H12 unconjugated

Western blot analysis using SPP1 mAb against human SPP1 recombinant protein. (Osteopontin Antikörper (AA 167-314))

Western blot analysis using SPP1 mAb against HEK293 (1) and SPP1 (AA: 167-314)-hIgGFc transfected HEK293 (2) cell lysate. (Osteopontin Antikörper (AA 167-314))

Black line: Control Antigen (100 ng), Purple line: Antigen(10 ng), Blue line: Antigen (50 ng), Red line: Antigen (100 ng), (Osteopontin Antikörper (AA 167-314))

ELISA

Immunohistochemical analysis of paraffin-embedded prostate cancer tissues using SPP1 mouse mAb with DAB staining. (Osteopontin Antikörper (AA 167-314))

IHC

Immunohistochemical analysis of paraffin-embedded endometrial cancer tissues using SPP1 mouse mAb with DAB staining. (Osteopontin Antikörper (AA 167-314))

IHC

5 Abbildungen

(2 Referenzen)

Produktnummer ABIN1098149

Datenblatt (PDF)

Target Alle Osteopontin (SPP1) Antikörper anzeigen

Osteopontin (SPP1) (Secreted phosphoprotein 1 (SPP1))
Bindungsspezifität
15

15

15

13

12

7

5

5

5

5

4

3

3

3

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 167-314
Reaktivität
137

71

61

9

5

4

4

2

2

1

1

1

1

1
Human
Wirt
119

47

5

4

2
Maus
Passende Sekundärantikörper
Klonalität
122

48
Monoklonal
Konjugat
84

14

13

8

7

4

3

3

3

3

3

3

3

3

3

3

3

2

2

2

2

2

2

1

1
Dieser Osteopontin Antikörper ist unkonjugiert
Applikation
142

72

46

39

39

24

19

17

14

13

9

7

4

3

2

2

2

2

1
ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Verwendungszweck

SPP1 Antibody

Aufreinigung

Purified antibody

Immunogen

Purified recombinant fragment of human SPP1 (AA: 167-314) expressed in E. Coli.

Klon

7C5H12

Isotyp

IgG1

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Applikationshinweise

ELISA: 1/10000
ICC: 1/200 - 1/1000

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Buffer

Purified antibody in PBS with 0.05 % sodium azide.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

4 °C,-20 °C

Informationen zur Lagerung

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Liersch, Gerss, Schliemann, Bayer, Schwöppe, Biermann, Appelmann, Kessler, Löwenberg, Büchner, Hiddemann, Müller-Tidow, Berdel, Mesters: "Osteopontin is a prognostic factor for survival of acute myeloid leukemia patients." in: Blood, Vol. 119, Issue 22, pp. 5215-20, (2012) (PubMed).

Wang, Wang, Tang: "Osteopontin expression in nasopharyngeal carcinoma: its relevance to the clinical stage of the disease." in: Journal of cancer research and therapeutics, Vol. 7, Issue 2, pp. 138-42, (2011) (PubMed).
Target

Osteopontin (SPP1) (Secreted phosphoprotein 1 (SPP1))

Andere Bezeichnung

SPP1 (SPP1 Produkte)

Synonyme

BNSP antikoerper, BSPI antikoerper, ETA-1 antikoerper, OPN antikoerper, 2AR antikoerper, Apl-1 antikoerper, Bsp antikoerper, Eta antikoerper, OP antikoerper, Opn antikoerper, Opnl antikoerper, Ric antikoerper, Spp-1 antikoerper, OSP antikoerper, zgc:111821 antikoerper, secreted phosphoprotein 1 antikoerper, SPP1 antikoerper, Spp1 antikoerper, spp1 antikoerper

Hintergrund

Description: The protein encoded by this gene is involved in the attachment of osteoclasts to the mineralized bone matrix. The encoded protein is secreted and binds hydroxyapatite with high affinity. The osteoclast vitronectin receptor is found in the cell membrane and may be involved in the binding to this protein. This protein is also a cytokine that upregulates expression of interferon-gamma and interleukin-12. Several transcript variants encoding different isoforms have been found for this gene.

Aliases: OPN, BNSP, BSPI, ETA-1

Molekulargewicht

35.4kDa

Gen-ID

6696

HGNC

6696

UniProt

P10451

Pathways

Regulation of Cell Size