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Cav3.1 Ca2+ Channel (AA 2052-2172), (C-Term) Antikörper

Reaktivität: Maus IHC, WB, IF/ICC Wirt: Maus Monoclonal S178A-9 unconjugated
Produktnummer ABIN1098196
  • Target
    Cav3.1 Ca2+ Channel
    Bindungsspezifität
    AA 2052-2172, C-Term
    Reaktivität
    • 1
    • 1
    • 1
    Maus
    Wirt
    • 1
    Maus
    Klonalität
    • 1
    Monoklonal
    Konjugat
    • 1
    Unkonjugiert
    Applikation
    Immunohistochemistry (IHC), Western Blotting (WB), Immunofluorescence (fixed cells) (IF/ICC)
    Verwendungszweck
    Anti-Cav3.1 Ca+2 Channel Mouse Monoclonal Antibody
    Spezifität
    This antibody recognizes human, mouse, and rat Cav3.1. It does not cross-react with Cav3.2.
    Kreuzreaktivität
    Human, Maus, Ratte
    Kreuzreaktivität (Details)
    No cross Reactivity with Cav3.2
    Aufreinigung
    Purified by Protein G affinity chromatography.
    Immunogen
    Fusion protein corresponding to aa 2052-2172 (cytoplasmic C-terminus) of mouse Cav3.1 (accession no. NP_001106284.1).
    Klon
    S178A-9
    Isotyp
    IgG1
  • Applikationshinweise
    Immunoblotting: use at 1-2 μg/mL. A band of >200 kDa is detected.
    Immunohistochemistry: use at 1-10 μg/mL.
    These are recommended concentrations. User should determine optimal concentrations for their application.
    Positive control: Rat brain membranes.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Rekonstitution
    Dilute in PBS or medium which is identical to that used in the assay system.
    Konzentration
    Lot specific
    Buffer
    PBS, pH 7.4, 50 % glycerol, 0.09 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    This antibody is stable for at least one (1) year at -20°C.
  • Target
    Cav3.1 Ca2+ Channel
    Andere Bezeichnung
    Cav3.1 Ca+2 Channel
    Hintergrund
    Voltage-dependent T-type calcium channel subunit α,Ion channels are integral membrane proteins that help establish and control the small voltage gradient across the plasma membrane of living cells by allowing the flow of ions down their electrochemical gradient. Cav3.1 is a low-voltage- activated T-type calcium channel expressed throughout the body. Drugs that block T-type calcium channels are used as antihypertensives and antiepileptics and possibly in some anesthetics and antipsychotics.
    NCBI Accession
    NP_001106284
    UniProt
    Q9WUT2
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