LPAR1 Antikörper (AA 342-359)

Produktnummer ABIN1101276

Produktdetails anti-LPAR1 Antikörper

Target: LPAR1 (Lysophosphatidic Acid Receptor 1 (LPAR1))

Bindungsspezifität: AA 342-359

Reaktivität: Human, Maus, Ratte, Affe, Fledermaus, Huhn, Rind (Kuh), Hund, Hamster, Pferd, Schwein, Schaf, Xenopus laevis

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LPAR1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Marke: IHC-plus™

Spezifität: Human lysophosphatidic acid 1 (LPA1) amino acids 342-359 (DRSASSLNHTILAGVHSN)

Homologie: Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Sheep, Hamster, Panda, Dog, Bat, Bovine, Horse, Pig, Opossum, Chicken, Platypus, Xenopus (100%) Elephant, Rabbit (94%).

Aufreinigung: Immunoaffinity purified

Immunogen: Human lysophosphatidic acid 1 (LPA1) amino acids 342-359 (DRSASSLNHTILAGVHSN). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Sheep, Hamster, Panda, Dog, Bat, Bovine, Horse, Pig, Opossum, Chicken, Platypus, Xenopus (100%), Elephant, Rabbit (94%).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Approved: ICC, IHC, IHC-P (10 μg/mL), WB

Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 10 μg/mL.

Kommentare:

Target Species of Antibody: Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Rekonstitution: 500 μL sterile water

Konzentration: Lot specific

Buffer: TBS,  pH 7.4, containing 50 % glycerol, 0.1 % BSA, and 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeat freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: Short term: -20°C
Long term: -20°C.

Details zu LPAR1

Target: LPAR1 (Lysophosphatidic Acid Receptor 1 (LPAR1))

Andere Bezeichnung: LPAR1 / LPA1 / EDG2 (LPAR1 Produkte)

Hintergrund: Name/Gene ID: LPAR1
Subfamily: Lysophospholipid/Lysosphingolipid
Family: GPCR

Synonyms: LPAR1, EDG-2, EDG2, Gpcr26, Rec.1.3, Vzg-1, Ventricular zone gene 1, LPA receptor 1, LPA-1, LPA1, Mrec1.3, VZG1

Gen-ID: 1902

UniProt: Q92633

Pathways: Myometrial Relaxation and Contraction, Smooth Muscle Cell Migration