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Angiopoietin 2 Antikörper (C-Term)
ANGPT2
Reaktivität: Human, Maus, Ratte
WB, IHC (p)
Wirt: Kaninchen
Polyclonal
unconjugated
Produktnummer ABIN1105366
Produktdetails anti-Angiopoietin 2 Antikörper
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Target
Alle Angiopoietin 2 (ANGPT2) Antikörper anzeigen
Angiopoietin 2 (ANGPT2)
Bindungsspezifität
Alle Epitope für Angiopoietin 2 Antikörper
C-Term
Reaktivität
Alle Reaktivitäten für Angiopoietin 2 Antikörper
Human, Maus, Ratte
Wirt
Alle Wirte für Angiopoietin 2 Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für Angiopoietin 2 Antikörper
Polyklonal
Konjugat
Alle Konjugate für Angiopoietin 2 Antikörper
Dieser Angiopoietin 2 Antikörper ist unkonjugiert
Applikation
Alle Applikationen für Angiopoietin 2 Antikörper
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Sequenz
Sequence is different from the related Mouse sequence by two amino acids.
Spezifität
This antibody detects Angiopoietin-2 near C-term. No cross reactivity with other proteins.
Kreuzreaktivität (Details)
Species reactivity (tested):Human, Mouse, Rat
Aufreinigung
Immunoaffinity Chromatography
Immunogen
Synthetic peptide corresponding to a sequence mapping near the C-terminal of Human Angiopoietin-2
Isotyp
IgG
Top Product
Discover our top product ANGPT2 Primärantikörper
Alternativen
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Anwendungsinformationen
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Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Rekonstitution
0.2 mL of distilled water will yield a concentration of 500 μg/mL.
Buffer
0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium Azide, 5 mg BSA
Konservierungsmittel
Thimerosal (Merthiolate)
Vorsichtsmaßnahmen
This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Avoid repeated freezing and thawing.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Details zu Angiopoietin 2
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Target
Angiopoietin 2 (ANGPT2)
Andere Bezeichnung
Angiopoietin-2 (ANGPT2 Produkte )
Synonyme
AGPT2 antikoerper, ANG2 antikoerper, Agpt2 antikoerper, Ang-2 antikoerper, Ang2 antikoerper, ang2 antikoerper, angpt2 antikoerper, ANGIOPOIETIN-2 antikoerper, ANG-2 antikoerper, ANGPT2 antikoerper, Angrp antikoerper, Rnase5b antikoerper, ANG3 antikoerper, C11orf2 antikoerper, C11orf3 antikoerper, FFR antikoerper, angiopoietin 2 antikoerper, angiopoietin 2b antikoerper, angiogenin, ribonuclease A family, member 2 antikoerper, VPS51, GARP complex subunit antikoerper, ANGPT2 antikoerper, Angpt2 antikoerper, angpt2b antikoerper, Ang2 antikoerper, VPS51 antikoerper
Hintergrund
Angiopoietin 1 and Angiopoietin 2 are important for development of the endothelium, by regulating tyrosine phosphorylation of the membrane receptor Tie 2. Angiopoietin 2 is only 60 % homologous with Angiopoietin 1. Angiopoietin-2 is a naturally occurring antagonist of angiopoietin-1 that competes for binding to the TIE2 receptor and blocks ANGPT1-induced TIE2 autophosphorylation. Angiopoietin 1 binding to Tie 2 causes phosphorylation of the receptor. Angiopoietin 2 competes for this binding, and thus blocks receptor phosphorylation. Angiopoietin 2 expression occurs at sites of vascular remodelling: dorsal aorta and major aortic branches, ovary, placenta and uterus.Synonyms: ANG-2, ANG2, ANGPT2
Gen-ID
11601
NCBI Accession
NP_031452
UniProt
O35608
Pathways
RTK Signalweg
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