Carboxy Methyl Lysine Antikörper
CML
EIA, WB, IHC (fro), IF, IHC (p)
Wirt: Maus
Monoclonal
CML26
unconjugated
-
- Target Alle Carboxy Methyl Lysine (CML) Antikörper anzeigen
- Carboxy Methyl Lysine (CML)
-
Wirt
- Maus
-
Klonalität
- Monoklonal
-
Konjugat
- Dieser Carboxy Methyl Lysine Antikörper ist unkonjugiert
- Applikation
- Enzyme Immunoassay (EIA), Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Kreuzreaktivität (Details)
- Species reactivity (tested):Human, Multispecies cross reactant.
- Aufreinigung
- Protein G Chromatography
- Immunogen
- Carboxy Methyl Lysine (CML)-KLH
- Klon
- CML26
- Isotyp
- IgG1
- Top Product
- Discover our top product CML Primärantikörper
-
-
- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Konzentration
- 0.1 mg/mL
- Buffer
- PBS, 0.02 % Sodium Azide, 0.1 % BSA
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C
- Informationen zur Lagerung
- Store undiluted at 2-8 °C.
-
- Target
- Carboxy Methyl Lysine (CML)
- Andere Bezeichnung
- Carboxy Methyl Lysine (CML Produkte)
- Synonyme
- ALL antikoerper, BCR1 antikoerper, CML antikoerper, D22S11 antikoerper, D22S662 antikoerper, PHL antikoerper, BCR, RhoGEF and GTPase activating protein antikoerper, BCR antikoerper
- Substanzklasse
- Amino Acid
- Hintergrund
- CML is known to be formed from the oxidation of both carbohydrates and lipids. This makes CML a biomarker of general oxidative stress. Carboxymethyl-lysine (CML) is a well-characterized glycoxidation product that accumulates in tissues with age, and its rate of accumulation is accelerated in diabetes. Glycoxidation products are a subset of advanced glycation endproducts (AGEs) that are formed by the nonenzymatic glycation and subsequent irreversible oxidation of proteins. Oxidative stress and protein modification have been implicated in the pathogenesis of the chronic complications of diabetes, including nephropathy and atherosclerosis. The accumulation of CML in long-lived tissue such as skin collagen reflects oxidative stress over an extended period of the life-span, and has been shown to be greater in patients with diabetic complications than those without complications.Synonyms: CML, Carboxymethyl-lysine
-
Sie sind hier:
