VCAM1 Antikörper
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- Target Alle VCAM1 Antikörper anzeigen
- VCAM1 (Vascular Cell Adhesion Molecule 1 (VCAM1))
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser VCAM1 Antikörper ist unkonjugiert
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Applikation
- Flow Cytometry (FACS), Functional Studies (Func), Enzyme Immunoassay (EIA)
- Spezifität
- Recognizes the Vascular Cellular Adhesion Molecule-1 (VCAM-1), a 110 kDa protein. Recognizes the soluble antigen.
- Kreuzreaktivität (Details)
- Species reactivity (tested):Human.
- Aufreinigung
- Ion Exchange Chromatography.
- Sterilität
- 0.22 μm filtered
- Immunogen
- Activated Human umbilical vein endothelial. cells. Hybridoma: Myeloma X63/AG.8653 x Balb/c spleen cells.
- Klon
- B-K9
- Isotyp
- IgG1
- Top Product
- Discover our top product VCAM1 Primärantikörper
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1.0 mg/mL
- Buffer
- Phosphate-buffered saline without Carrier and preservatives. This prodcut is sterile-filtered through 0.22 μm and treated to remove Endotoxins.
- Konservierungsmittel
- Without preservative
- Lagerung
- 4 °C
- Informationen zur Lagerung
- Store the antibody undiluted at 2-8 °C.
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- Target
- VCAM1 (Vascular Cell Adhesion Molecule 1 (VCAM1))
- Andere Bezeichnung
- CD106 / VCAM1 (VCAM1 Produkte)
- Hintergrund
- CD106 / VCAM-1 (vascular cell adhesion molecule-1) is an Ig-like cell surface adhesion molecule binding VLA-4 integrin. VCAM-1 is a potent T cell costimulatory molecule taking part in their positive selection and survival, as well as in adhesion, transendothelial migration and activation of peripheral T cells. VCAM-1 is also involved in endothelial cell-cell contacts. Whereas VCAM-1 normally mediates leukocyte extravasion to sites of tissue inflammation, tumour cells can use overexpressed VCAM-1 to escape T cell immunity. Soluble form of VCAM-1 (sVCAM-1) is an inflammatory marker and can be used also in prognosis of subsequent cariovascular events following acute coronary syndromes.Synonyms: INCAM-100, L1CAM, V-CAM 1, VCAM-1, Vascular cell adhesion protein 1
- Gen-ID
- 7412
- NCBI Accession
- NP_001069
- UniProt
- P19320
- Pathways
- Carbohydrate Homeostasis
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