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ITGAL Antikörper

ITGAL Reaktivität: Human FACS, IF, IHC (fro) Wirt: Maus Monoclonal DF1524 unconjugated
Produktnummer ABIN1105766
  • Target Alle ITGAL Antikörper anzeigen
    ITGAL (Integrin alpha-L (ITGAL))
    Reaktivität
    • 133
    • 72
    • 19
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 105
    • 59
    • 46
    • 1
    Maus
    Klonalität
    • 156
    • 54
    • 1
    Monoklonal
    Konjugat
    • 70
    • 30
    • 25
    • 20
    • 11
    • 7
    • 6
    • 6
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser ITGAL Antikörper ist unkonjugiert
    Applikation
    • 138
    • 47
    • 35
    • 31
    • 30
    • 25
    • 23
    • 18
    • 10
    • 8
    • 6
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Spezifität
    This antibody specifically detects CD11a positive leucocytes. CD11a antigens are expressed on lymphocytes, granulocytes, monocytes and macrophages with increased levels on memory T cells (1,2). Clone DF1524 was clustered at the Leucovyte Typing Workshop IV (5).
    Aufreinigung
    Affinity chromatography
    Klon
    DF1524
    Isotyp
    IgG2b
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  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    0.1 mg / ml
    Buffer
    0.01 M sodium phosphate, 0.15 M NaCl, pH 7.3, 0.2 % BSA, 0.09 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store the antibody undiluted at 2-8 °C.
  • Target
    ITGAL (Integrin alpha-L (ITGAL))
    Andere Bezeichnung
    CD11a / ITGAL (ITGAL Produkte)
    Synonyme
    CD11A antikoerper, LFA-1 antikoerper, LFA1A antikoerper, (p180) antikoerper, Cd11a antikoerper, LFA-1A antikoerper, Ly-15 antikoerper, Ly-21 antikoerper, CD11a antikoerper, ITGAL antikoerper, integrin subunit alpha L antikoerper, integrin alpha L antikoerper, ITGAL antikoerper, Itgal antikoerper
    Hintergrund
    CD11a/CD18 was first described as an accessory molecule in cytotoxic lymphocyte killing. CD11a (Integrin alpha-L) combines with CD18 (Integrin beta-2) to form the integrin LFA-1. LFA-1 mediates adhesion of lymphoid cells to the vascular endothelium in association with its ligands. The avidity of CD11a to its ligands is transiently upregulated on T cells upon activation (3). CD11a has also been shown to bind bacterial lipopolysaccarides (4).Synonyms: CD11 antigen-like family member A, Integrin alpha-L, LFA-1, LFA1, Leukocyte adhesion glycoprotein LFA-1 alpha chain, Leukocyte function-associated molecule 1 alpha chain
    Gen-ID
    3683
    NCBI Accession
    NP_002200
    UniProt
    P20701
    Pathways
    Activated T Cell Proliferation, Integrin Complex
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