Leptin Receptor Antikörper (Soluble)
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- Target Alle Leptin Receptor (LEPR) Antikörper anzeigen
- Leptin Receptor (LEPR)
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Bindungsspezifität
- Soluble
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser Leptin Receptor Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)
- Kreuzreaktivität (Details)
- Species reactivity (tested):Human
- Aufreinigung
- Protein G
- Klon
- 2F1
- Isotyp
- IgG1
- Top Product
- Discover our top product LEPR Primärantikörper
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 0.1 mg/mL
- Buffer
- PBS, 0.02 % sodium azide, 0.1 % bovine serum albumin
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C
- Informationen zur Lagerung
- Store at 2 - 8 °C.
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- Target
- Leptin Receptor (LEPR)
- Andere Bezeichnung
- CD295 / Leptin Receptor (LEPR Produkte)
- Synonyme
- CD295 antikoerper, LEP-R antikoerper, LEPRD antikoerper, OB-R antikoerper, OBR antikoerper, obr antikoerper, cd295 antikoerper, ob-rb antikoerper, Fa antikoerper, LEPROT antikoerper, Leprb antikoerper, Modb1 antikoerper, OB-RGRP antikoerper, Obr antikoerper, db antikoerper, diabetes antikoerper, obese-like antikoerper, obl antikoerper, ObRb antikoerper, Ob-R antikoerper, Ob-RM antikoerper, lepr antikoerper, leptin receptor antikoerper, leptin receptor S homeolog antikoerper, LEPR antikoerper, lepr antikoerper, Lepr antikoerper, lepr.S antikoerper
- Hintergrund
- Leptin is a cytokine that is primarily expressed by adipose tissue. Leptin controls food intake by its interaction with the leptin receptor in the brain. Leptin action is mediated and controlled by the leptin receptor, a class I type cytokine receptor. sLR is generated by proteolytic cleavage of membrane-anchored receptors. This indicates that the leptin receptor might have other functions besides transduction. Binding of leptin with sLR increases the bioavailability of leptin in plasma, but also decreases the binding of leptin to membrane bound leptin receptors. For example, when comparing obese and lean individuals, plasma levels of sLR are significantly decreased whereas leptin levels are significantly increased.Synonyms: DB, HuB219, LEP-R, LEPR, OB receptor, OB-R, OBR
- Gen-ID
- 9606
- UniProt
- P48357
- Pathways
- JAK-STAT Signalweg, AMPK Signaling, Feeding Behaviour
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