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Transferrin Receptor Antikörper

TFRC Reaktivität: Human WB, IP, IHC (fro), EIA Wirt: Maus Monoclonal 3B8 2A1 unconjugated

Produktnummer ABIN1106549

Datenblatt (PDF)

Target Alle Transferrin Receptor (TFRC) Antikörper anzeigen

Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))
Reaktivität
202

89

33

7

5

4

4

4

4

2

2

2

1
Human
Wirt
121

111

35

1

1
Maus
Passende Sekundärantikörper
Klonalität
171

94

3
Monoklonal
Konjugat
123

27

23

16

10

5

4

4

3

3

3

3

3

3

3

3

3

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Dieser Transferrin Receptor Antikörper ist unkonjugiert
Applikation
161

134

70

66

60

41

26

24

20

12

7

5

4

3

3

3

3

2

2

2

1

1

1

1

1

1

1

1

1

1
Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)

Spezifität

This antibody detects Transferrin receptor 1.

Kreuzreaktivität (Details)

Species reactivity (tested):Human

Aufreinigung

Protein G

Klon

3B8 2A1

Isotyp

IgG1

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TFRC Reaktivität: Human FACS, WB, IHC (p) Wirt: Kaninchen Polyclonal RB20736 unconjugated

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TFRC Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal 1A1B2 unconjugated

anti-Transferrin Receptor (p90, CD71) (TFRC) (AA 567-744) antibody
TFRC Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-Transferrin Receptor (p90, CD71) (TFRC) (AA 572-757) antibody
TFRC Reaktivität: Maus WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated

Applikationshinweise

Optimal working dilution should be determined by the investigator.

Beschränkungen

Nur für Forschungszwecke einsetzbar
Konzentration

0.1 mg/mL

Buffer

PBS, 0.02 % sodium azide, 0.1 % bovine serum albumin

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

4 °C

Informationen zur Lagerung

Store at 2 - 8 °C.
Target

Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

Andere Bezeichnung

CD71 / TFRC (TFRC Produkte)

Hintergrund

Human transferrin receptor 1 (TfR1), also designated CD71, is a homodimeric type II membrane glycoprotein of 90-95 kDa. This receptor binds two molecules of the serum iron-transport protein transferrin (Tf) and is internalised into endosomes that are acidified, resulting in the release of iron from Tf. TfR1 is not expressed on resting leukocytes but is upregulated on all proliferating cells upon activation, reflecting the iron dependence of proliferation. In tissues TfR1 is expressed on most dividing cells and on brain capillary endothelium. Expression of TfR1 is down regulated as a result of iron overload. TfR1 shares 45 % identity with TfR2.Synonyms: TfR1, Transferrin receptor protein 1, p90

Gen-ID

7037

NCBI Accession

NP_001121620

UniProt

P02786

Pathways

Transition Metal Ion Homeostasis