Basal Cell Cytokeratin Antikörper

Produktnummer ABIN1106892

Produktdetails

Target: Basal Cell Cytokeratin

Reaktivität: Human, Kaninchen, Ratte, Meerschweinchen, Schwein, Wachtel, Huhn, Hund, Zebrafisch (Danio rerio), Hamster

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (IF)

Spezifität: Clone RCK103 is a Cytokeratin antibody recognizing (amongst others) Cytokeratin 5. This monoclonal antibody stains basal cells in combined and stratified epithelial tissues. It recognizes the stem cell population, including the so-called amplifying cells in the prostate epithelium.

Kreuzreaktivität (Details): Species reactivity (tested):Canine, Chicken, Guinea Pig, Hamster, Human, Quail, Rabbit, Rat, Swine, Zebrafish.

Aufreinigung: Purified

Immunogen: A mix of cell preparations containing Human cytokeratins.

Klon: RCK103

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS, 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody undiluted (protected from light) at 2-8 °C Do Not Freeze!

Antigendetails

Target: Basal Cell Cytokeratin

Andere Bezeichnung: Cytokeratin (Basal Cell)

Hintergrund: Cytokeratins are a subfamily of intermediate filament proteins and are characterized by a remarkable biochemical diversity, represented in human epithelial tissues by at least 20 different polypeptides. They range in molecular weight between 40 kDa and 68 kDa and isoelectric pH between 4.9 - 7.8. The individual human cytokeratins are numbered 1 to 20. The various epithelia in the human body usually express cytokeratins which are not only characteristic of the type of epithelium, but also related to the degree of maturation or differentiation within an epithelium. Cytokeratin subtype expression patterns are used to an increasing extent in the distinction of different types of epithelial malignancies. The cytokeratin antibodies are not only of assistance in the differential diagnosis of tumors using immunohistochemistry on tissue sections, but are also a useful tool in cytopathology and flow cytometric assays.