Histone H2A Antikörper

Produktnummer ABIN1107544

Produktdetails anti-Histone H2A Antikörper

Target: Histone H2A

Reaktivität: Human, Ratte, Maus, Hamster

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Histone H2A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP)

Kreuzreaktivität (Details): Species reactivity (tested):Human, mouse, rat, hamster

Aufreinigung: Protein A agarose

Immunogen: Protein fraction extracted from the mitotic chromosome

Klon: C10037

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS

Konservierungsmittel: Azide free

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store (in aliquots) at -20 °C.

Details zu Histone H2A

Target: Histone H2A

Abstract: Histone H2A Produkte

Synonyme: 5499 antikoerper, CG5499 antikoerper, Dmel\\CG5499 antikoerper, H2A antikoerper, H2A.F/Z antikoerper, H2A.X antikoerper, H2A.Z antikoerper, H2AV antikoerper, H2AV_DROM antikoerper, H2AX antikoerper, H2AZ antikoerper, H2Av antikoerper, H2AvD antikoerper, H2a.V antikoerper, H2av antikoerper, H2avD antikoerper, HIS antikoerper, HIS2AV antikoerper, HIS2AVD antikoerper, His antikoerper, His2 antikoerper, His2AV antikoerper, His2AvD antikoerper, HisH2Av antikoerper, Hist antikoerper, Hist2av antikoerper, gamma-H2Av antikoerper, gamma-HIS2AV antikoerper, gamma-His2Av antikoerper, gammaH2Av antikoerper, h2AvD antikoerper, his antikoerper, l(3)05146 antikoerper, l(3)810 antikoerper, l(3)97Dd antikoerper, l(3)L1602 antikoerper, DDBDRAFT_0205974 antikoerper, DDBDRAFT_0216271 antikoerper, DDB_0205974 antikoerper, DDB_0216271 antikoerper, RGD1564767 antikoerper, H2a-221 antikoerper, H2A-III antikoerper, HIST1H2AA antikoerper, Histone H2A variant antikoerper, putative histone H2A antikoerper, histone H2A antikoerper, histone cluster 1 H2A family member F antikoerper, histone H2A-like antikoerper, histone cluster 1, H2af antikoerper, histone2A1 antikoerper, histone cluster 1, H2A, III antikoerper, histone cluster 1, H2ac antikoerper, His2Av antikoerper, LMJF_17_0280 antikoerper, H2AX antikoerper, Hist1h2af antikoerper, LOC100425378 antikoerper, his2a1 antikoerper, HIST1H2A3 antikoerper, HIST1H2AC antikoerper, h2a-A antikoerper

Hintergrund: The nucleosome is made up of four core histone proteins (H2A, H2B, H3 and H4) and is the primary building block of chromatin. The N-terminal tail of core histones undergoes multIPPle different post-translational modifications including acetylation, phosphorylation, ubiquitination, methylation and ADP-ribosylation. These modifications occur in response to cell signal stimuli and have a direct effect on gene expression. The role of histone variants, and specially those of H3 and H2A, in various nuclear processes has been long appreciated. There are at least three different families of H2A variants present in a variety of organisms from yeast to mammals, and the degree of conservation among members of each family is greater than that of the canonical H2A. H2AX is thought to play a role in DNA double-strand break repair, the serine in the SQEY motif of H2AX is phosphorylated at the site of the DNA damage and serves as a signal for the recruitment of repair proteins. Macro H2A1, another H2A variant, has been shown to have a role in X-chromosome inactivation and dosage compensation in mammals, where it is found to localize to the inactive X after silencing has been established.Synonyms: H2A Histone Family, HIST1H2A

Molekulargewicht: 14 kDa