MBP/MBL Antikörper

Produktnummer ABIN1108118

Produktdetails anti-MBP/MBL Antikörper

Target: MBP/MBL (Mannan Binding Protein/Mannan Binding Lectin (MBP/MBL))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser MBP/MBL Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA), Neutralization (Neut)

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Klon: 3-00E-007

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0,1 mg/mL

Buffer: PBS, 0,02 % sodium azide, 0,1 % BSA

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C.

Details zu MBP/MBL

Target: MBP/MBL (Mannan Binding Protein/Mannan Binding Lectin (MBP/MBL))

Andere Bezeichnung: Mannan Binding Protein (MBP/MBL Produkte)

Synonyme: COLEC1 antikoerper, HSMBPC antikoerper, MBL antikoerper, MBL2D antikoerper, MBP antikoerper, MBP-C antikoerper, MBP1 antikoerper, MBPD antikoerper, pMBP-27 antikoerper, MBL1 antikoerper, cMBl antikoerper, collectin antikoerper, L-MBP antikoerper, MBL-C antikoerper, RaRF p28A antikoerper, mbl antikoerper, mannose binding lectin 2 antikoerper, mannose-binding lectin (protein C) 2 antikoerper, mannose-binding protein C-like antikoerper, MBL2 antikoerper, Mbl2 antikoerper, LOC100911854 antikoerper

Hintergrund: Mannose Binding Lectin (MBL) also called mannose- or mannan-binding protein (MBP) is a member of the group of Collectins. MBL is an oligomeric lectin that recognizes carbohydrates as mannose and N-acetylglucosamine on pathogens. MBL contains a cysteine rich, a collagen like and a carbohydrate recognition domain. It forms a complex with C1r/C1s like serine proteases designated MASPs that proteolytically cleave C4, C2 and C3. MBL is able to activate the complement pathway independent of the classical and alternative complement activation pathways. The MBL-MASP pathway (better known as the lectin pathway) is antibody and C1q-independent. MBL exhibits complement-dependent antibacterial activity and acts directly as an opsonic and therefore plays an important role in innate immunity. MBL is synthesized by hepatocytes and has been isolated from the liver or serum of various vertebrate species.Synonyms: MBL, MBL2, MBP, MBP-C, MBP1, Mannan-binding protein, Mannose-binding lectin, Mannose-binding protein C

Gen-ID: 9606

UniProt: P11226