MEAF6 Antikörper (N-Term)

Produktnummer ABIN1108194

Produktdetails anti-MEAF6 Antikörper

Target: MEAF6 (MYST/Esa1-Associated Factor 6 (MEAF6))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Zebrafisch (Danio rerio), Xenopus laevis, Huhn

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MEAF6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Sequenz: HNKAAPPQIP DTRRELAELV KRKQELAETL ANLERQIYAF EGSYLEDTQM

Kreuzreaktivität (Details): Species reactivity (expected):Mouse, Rat, Bovine, Chicken, African clawed frog, ZebrafishSpecies reactivity (tested):Human

Aufreinigung: Purified using peptide immunoaffinity column

Immunogen: The immunogen for anti-MEAF6 antibody: synthetic peptide directed towards the N terminal of human MEAF6

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: Add 50 μL of distilled water to a final concentration of 1 mg/mL.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store lyophilized at 2-8 °C or at -20 °C long term. After reconstitution store the antibody undiluted at 2-8 °C for up to one month or in aliquots at -20 °C long term.

Details zu MEAF6

Target: MEAF6 (MYST/Esa1-Associated Factor 6 (MEAF6))

Andere Bezeichnung: MEAF6 (MEAF6 Produkte)

Hintergrund: MEAF6 is a component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. Component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo.Synonyms: C1orf149, Chromatin modification-related protein MEAF6, EAF6, EAF6 homolog, Esa1-associated factor 6 homolog, MYST/Esa1-associated factor 6, NY-SAR-91, Sarcoma antigen NY-SAR-91

Gen-ID: 64769

NCBI Accession: NP_073593