NFE2L3
Reaktivität: Human
WB
Wirt: Kaninchen
Polyclonal
unconjugated
Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Rekonstitution
Add 50 μL of distilled water to a final concentration of 1 mg/mL
Handhabung
Avoid repeated freezing and thawing.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store lyophilized at 2-8 °C or at -20 °C long term. After reconstitution store the antibody undiluted at 2-8 °C for up to one month or in aliquots at -20 °C long term.
NFE2L3 belongs to the bZIP family, CNC subfamily, and activates erythroid-specific, globin gene expression. It forms heterodimers with MAFG, MAFK and other small MAF proteins that binds to the MAF recognition elements (MARE). NFE2L3 also called NRF3 is highly expressed in human placenta and also in B-cell and monocyte cell lines. Low expression is observed in heart, brain, lung, skeletal muscle, kidney and pancreas.Synonyms: NF-E2-related factor 3, NFE2-related factor 3, NRF3, Nuclear factor erythroid 2-related factor 3