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Polymyxin B Antikörper

Reaktivität: Bacillus polymyxa WB, EIA Wirt: Maus Monoclonal 45 unconjugated
Produktnummer ABIN1108692
  • Target Alle Polymyxin B Produkte
    Polymyxin B
    Reaktivität
    Bacillus polymyxa
    Wirt
    • 1
    Maus
    Klonalität
    • 1
    Monoklonal
    Konjugat
    • 1
    Dieser Polymyxin B Antikörper ist unkonjugiert
    Applikation
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Endotoxin-Niveau
    Low Endotoxin
    Klon
    45
    Isotyp
    IgM
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    > 0.2 mg/mL
    Buffer
    0.02 % Sodium Azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    Polymyxin B
    Abstract
    Polymyxin B Produkte
    Hintergrund
    The peptide antibiotic Polymyxin B (PMB) binds to bacterial endotoxin (lipopolysaccharide, LPS). The interaction of PMB with LPS involves ionic forces between amino groups in PMB and negatively charged phosphate and carboxyl groups in the lipid A-Kdo region. PMB has relevance for endotoxin research in at least two ways: first, PMB reacts with LPS of many species regardless of varied serospecificity, and thus it can be used as a general probe for measuring or detecting LPS or lipid A. Second, binding of PMB to LPS may result in neutralization of the detrimental effects of LPS either in vitro or in vivo.
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