SYT1 Antikörper
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- Target Alle SYT1 Antikörper anzeigen
- SYT1 (Synaptotagmin I (SYT1))
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Reaktivität
- Ratte
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser SYT1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP)
- Spezifität
- This antibody reacts with Synaptotagmin 1 and 2 (58 kDa/60 kDa) on Western blotting. Synaptotagmin 1 has a predicted molecular weight of 47 kDa but it migrates at ~65 kDa. It is reported that this clone (1D12) recognizes rat synaptotagmin residues (99-104 aa) in the reference number 17).
- Kreuzreaktivität (Details)
- Species reactivity (tested):Rat
- Aufreinigung
- Protein A agarose
- Immunogen
- Chicken brain synaptic membrane
- Klon
- 1D12
- Isotyp
- IgG2a
- Top Product
- Discover our top product SYT1 Primärantikörper
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anti-Synaptotagmin I (SYT1) (AA 1-422) antibody
SYT1 Reaktivität: Human WB, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Synaptotagmin I (SYT1) (AA 136-422) antibodySYT1 Reaktivität: Human WB, IHC, ICC, IP Wirt: Kaninchen Polyclonal unconjugated
anti-Synaptotagmin I (SYT1) antibodySYT1 Reaktivität: Human, Ratte, Maus WB, IHC (p), FACS Wirt: Kaninchen Polyclonal unconjugated
anti-Synaptotagmin I (SYT1) (AA 1-422) antibodySYT1 Reaktivität: Human WB, ELISA, IF Wirt: Maus Monoclonal 3A5 unconjugated
anti-Synaptotagmin I (SYT1) (pSer309) antibodySYT1 Reaktivität: Ratte WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Synaptotagmin I (SYT1) antibodySYT1 Reaktivität: Human, Ratte, Maus WB, IHC, ICC, IHC (fro), FACS Wirt: Kaninchen Polyclonal unconjugated
anti-Synaptotagmin I (SYT1) antibodySYT1 Reaktivität: Human, Ratte, Maus IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Synaptotagmin I (SYT1) (AA 1-422) antibodySYT1 Reaktivität: Human WB, ELISA, IHC (p) Wirt: Maus Monoclonal 1A6 unconjugated
anti-Synaptotagmin I (SYT1) (AA 301-523) antibodySYT1 Reaktivität: Human IHC, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-Synaptotagmin I (SYT1) (pThr202) antibodySYT1 Reaktivität: Human WB, IHC, ELISA Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1.0 mg/mL
- Buffer
- PBS containing 50 % glycerol, pH 7.2, without preservatives
- Konservierungsmittel
- Without preservative
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store (in aliquots) at -20 °C.
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- Target
- SYT1 (Synaptotagmin I (SYT1))
- Andere Bezeichnung
- Synaptotagmin-1 (SYT1 Produkte)
- Hintergrund
- Synaptotagmins are a family of at least 15 Ca2+-binding, membrane-trafficking proteins that act as calcium sensors regulating neurotransmitter release. Synaptotagamins are expressed in both vesicular and plasma membranes where they are involved in lipid rearrangements required during synaptic vesicle fusion. Synaptotagmins also interact with calcium channels, sodium channels, b-SNAP, neurexins, and other neural proteins in the absence of Ca2+, suggesting a role in presynaptic functions. Synaptotagmins exhibit differential expression, with synaptotagmins 1-5 expressed primarily in neural and endocrine tissues. Northern blots in murine brain tissue suggest synaptotagmin 1 is primarily expressed in rostral brain regions but has low expression in regions related to motor functions.Synonyms: SVP65, SYT, SYT2, Synaptotagmin I, Synaptotagmin II, Synaptotagmin1, Synaptotagmin2, Synonyms: SYT1, SytI, SytII, p65
- Gen-ID
- 6857
- NCBI Accession
- NP_001129277
- UniProt
- P21579
- Pathways
- Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport
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