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TIMP3 Antikörper (C-Term)
TIMP3
Reaktivität: Human, Ratte, Maus
WB
Wirt: Kaninchen
Polyclonal
unconjugated
Produktnummer ABIN1109258
Produktdetails anti-TIMP3 Antikörper
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Target
Alle TIMP3 Antikörper anzeigen
TIMP3
(TIMP Metallopeptidase Inhibitor 3 (TIMP3))
Bindungsspezifität
Alle Epitope für TIMP3 Antikörper
C-Term
Reaktivität
Alle Reaktivitäten für TIMP3 Antikörper
Human, Ratte, Maus
Wirt
Alle Wirte für TIMP3 Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für TIMP3 Antikörper
Polyklonal
Konjugat
Alle Konjugate für TIMP3 Antikörper
Dieser TIMP3 Antikörper ist unkonjugiert
Applikation
Alle Applikationen für TIMP3 Antikörper
Western Blotting (WB)
Spezifität
This antibody detects TIMP3 (C-term). No cross reactivity with other proteins.
Kreuzreaktivität (Details)
Species reactivity (tested):Human, mouse, rat
Aufreinigung
Immunogen affinity purified
Immunogen
A peptide mapping at the C-terminal end of TIMP-3 of human origin .Remarks: Sequence is different to the related rat sequence by single amino acid.
Isotyp
IgG
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Anwendungsinformationen
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Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Rekonstitution
0.2 mL of distilled water will yield a concentration of 500 μg/mL.
Buffer
5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3
Konservierungsmittel
Sodium azide, Thimerosal (Merthiolate)
Vorsichtsmaßnahmen
This product contains Sodium azide and Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Handhabung
Avoid repeated freezing and thawing.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
Details zu TIMP3
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Target
TIMP3
(TIMP Metallopeptidase Inhibitor 3 (TIMP3))
Andere Bezeichnung
TIMP3 (TIMP3 Produkte )
Synonyme
TIMP-3 antikoerper, TIMP3 antikoerper, timp3 antikoerper, HSMRK222 antikoerper, K222 antikoerper, K222TA2 antikoerper, SFD antikoerper, IMP-3 antikoerper, timp3-A antikoerper, Timp-3 antikoerper, metalloproteinase inhibitor 3 antikoerper, TIMP metallopeptidase inhibitor 3 antikoerper, Metalloproteinase inhibitor 3 antikoerper, TIMP metallopeptidase inhibitor 3 L homeolog antikoerper, tissue inhibitor of metalloproteinase 3 antikoerper, CpipJ_CPIJ003282 antikoerper, TIMP3 antikoerper, timp3 antikoerper, Timp3 antikoerper, timp3.L antikoerper
Hintergrund
The tissue inhibitors of metalloproteinases (TIMPs) are natural inhibitors of the matrix metalloproteinases, a group of zinc-binding endopeptidases involved in the degradation of the extracellular matrix. The TIMP3 gene is expressed in many tissues, with highest expression in the placenta. TIMP3 encodes a potent angiogenesis inhibitor and is mutated in Sorsby fundus dystrophy, a macular degenerative disease with submacular choroidal neovascularization. TIMP3 gene is mapped to 22q12.1-q13.2. Mutations in TIMP3 cause the autosomal dominant disorder Sorsby's fundus dystrophy (SFD).Synonyms: Metalloproteinase inhibitor 3, Protein MIG-5, TIMP-3, Tissue inhibitor of metalloproteinases 3
Gen-ID
7078
NCBI Accession
NP_000353
UniProt
P35625
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