F11
Reaktivität: Human
WB, EIA
Wirt: Kaninchen
Polyclonal
unconjugated
Applikationshinweise
Inhibitory in clotting assays. Useful for purification of Factor XI. Western blot (non-reduced samples only, band size 160 kD). RIA. ELISA. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Konzentration
12.4 mg/mL (OD280 nm, E1% = 14)
Buffer
50 % (vol/vol) glycerol/water) without preservatives
Konservierungsmittel
Without preservative
Handhabung
This product is photosensitive and should be protected from light
Factor X is activated by the cleavage of the activation peptide by factor IXa (in the intrisic pathway), or by factor VIIa (in the extrinsic pathway). The activated factor then converts prothrombin to thrombin in the presence of factor Va, Ca+2, and phospholipid during blood clotting. Mutations of this gene result in factor X deficiency, a haemorrhagic condition of variable severity.Synonyms: FX1, PTA, Plasma thromboplastin antecedent