HBsAg
Reaktivität: Hepatitis B Virus (HBV)
ELISA, LA
Wirt: Maus
Monoclonal
B-53
unconjugated
Applikationshinweise
Detection of HBsAg in two-site enzyme Immunoassay. Use this antibody as Capture in ELISA and BM3320 for Detection. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Konzentration
3.9 mg/mL (OD280 nm, E0.1% = 1.4)
Buffer
PBS, pH 7.4 with 0.09 % Sodium Azide as preservative.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C
Informationen zur Lagerung
Store the antibody undiluted at 2-8 °C.
Target
HBSAg (HBsAg)
(Hepatitis B Virus Surface Antigen (HBsAg))
Hepatitis B Virus (HBV) infection induces a disease state which manifests itself in a variety of ways, characterized by the extent of liver damage, inflammation and viral persistence. HBV infection is also associated with a 100 fold increased risk of hepatocellular carcinoma and currently infects over 250 million people worldwide. HBV has a partially double stranded 3.2 kilobase DNA genome which contains four open reading frames. One of these encodes a 154 amino acid protein called the HBx protein. HBx has been shown to be a transcriptional transactivator of both viral and cellular promoters. Lacking a DNA binding domain and nuclear localization signal, HBx is believed to exert transcriptional activity through protein protein interaction.Synonyms: HBV surface antigen, Hepatitis B Virus