HCV NS5 Antikörper (AA 2190-2300)
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- Target Alle HCV NS5 Produkte
- HCV NS5 (Hepatitis C Virus NS5 (HCV NS5))
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Bindungsspezifität
- AA 2190-2300
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Reaktivität
- Hepatitis C Virus (HCV)
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser HCV NS5 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Aufreinigung
- Protein G Chromatography.
- Immunogen
- Recombinant antigen (HCV) genotype 1b. Remarks:
- Klon
- 7-D4
- Isotyp
- IgG1
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- Applikationshinweise
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Suitable for use in ELISA (approx. 10e-6), Western Blot (1/1000) and Immunohistochemistry(Cryostat liver sections: 1/20).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1.0 mg/mL
- Buffer
- PBS, pH 7.2 containing 0.01 % Sodium Azide as preservative.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store the antibody at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Do not freeze working dilutions
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- Target
- HCV NS5 (Hepatitis C Virus NS5 (HCV NS5))
- Andere Bezeichnung
- HCV NS5 (HCV NS5 Produkte)
- Substanzklasse
- Viral Protein
- Hintergrund
- HCV is classified into the genus Hepacivirus of the family Flaviviridae. Like all the members of the family, HCV is an enveloped, single-stranded, positive-sense RNA virus. Its genome (about 9600 nt) is flanked at both termini by conserved, highly structured non-translated regions (NTRs) and encodes a polyprotein precursor (about 3000 aa), which is proteolytically processed by host and viral proteases to produce the structural (core, E1, E2 and p7) and non-structural (NS2, NS3, NS4A, NS4B, NS5A and NS5B) proteins of the virus. Recently, an additional protein has been identified, whose function remains unknown. NS5A is a ~56 kDa pleiotropic protein with key roles in both viral RNA replication and modulation of the physiology of the host cellSynonyms: Hepatitis C Virus Non-structural protein NS5A
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