Keratin 3 Antikörper

Produktnummer ABIN112318

Produktdetails anti-Keratin 3 Antikörper

Target: Keratin 3 (KRT3)

Reaktivität: Human, Kaninchen, Rind (Kuh)

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Keratin 3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro))

Spezifität: Cytokeratin 3 antibody, clone AE5 represents an excellent marker for corneal type differentiation. Positive for epithelial cells of cornea, snout and some oral mucosa. This antibody has been used for studying corneal epithelial stem cells. Polypeptide Reacting: Mr 64 000 polypeptide (Keratin K3, formerly also designated Cytokeratin 3) of human corneal epithelium and Keratin K76 (formerly also designated Cytokeratin K2p) of palate epithelium. Reactivities on Cultured Cell Lines: Rabbit corneal epithelial cells. In Cow and Rabbit it reacts with lip and snout epithelia.

Kreuzreaktivität (Details): Species reactivity (tested):Human, Rabbit and Bovine.

Aufreinigung: Ion Exchange Chromatography.

Immunogen: Human epithelial keratin

Klon: AE5

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Immunoblotting: 1/500. Immunohistochemistry on Frozen Sections: 1/50 (1h at RT).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS, pH 7,2 containing 0.09 % Sodium Azide as preservative.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu Keratin 3

Target: Keratin 3 (KRT3)

Andere Bezeichnung: Cytokeratin 3 (KRT3 Produkte)

Synonyme: CK3 antikoerper, K3 antikoerper, CK-3 antikoerper, keratin 3 antikoerper, KRT3 antikoerper

Hintergrund: Cytokeratin 3 belongs to the intermediate filament family. It is a type II cytokeratin and is specifically expressed in the corneal epithelium. Cytokeratin 3 associates with Cytokeratin 12. Defects in Cytokeratin 3 are a cause of Meesmann corneal dystrophy.Synonyms: 65 kDa cytokeratin, KRT3, Keratin, Type-II keratin Kb3, keratin-3, keratin-76, type II cytoskeletal 3

Gen-ID: 3850

NCBI Accession: NP_476429

UniProt: P12035