EPO Antikörper
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- Target Alle EPO Antikörper anzeigen
- EPO (Erythropoietin (EPO))
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser EPO Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA), Functional Studies (Func)
- Spezifität
- This antibody reacts with Erythropoietin, the principal hormone involved in the regulation of erythrocyte differentiation and the maintenance of a physiological levels of circulating erythrocyte mass. It is often used as a drug to treat anemia.
- Aufreinigung
- Affinity Chromatography on Protein A
- Immunogen
- CHO cell-derived, recombinant Human Erythropoietin.
- Top Product
- Discover our top product EPO Primärantikörper
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- Applikationshinweise
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ELISA: 0.5-1 μg/mL. Western Blot: 1-2 μg/mL (Reducing and Non-Reducing Conditions). Functional Assays: The ND50 was determined to be approximately 1-3 μg/mL, in thepresence of 0.3 units/mL of rhEpo, using a Human factor dependant cell line. Immunohistochemistry on Paraffin Sections: 15 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1.0 mg/mL
- Buffer
- PBS, pH 7.2, 0.09 % Sodium Azide, 5 % Trehalose
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Target
- EPO (Erythropoietin (EPO))
- Andere Bezeichnung
- Erythropoietin / EPO (EPO Produkte)
- Synonyme
- EPO antikoerper, EP antikoerper, MVCD2 antikoerper, erythropoietin antikoerper, erythropoietin S homeolog antikoerper, erythropoietin a antikoerper, EPO antikoerper, epo antikoerper, epo.S antikoerper, Epo antikoerper, epoa antikoerper
- Substanzklasse
- Hormone
- Hintergrund
- Human erythropoietin is member of the EPO/TPO family and encodes a secreted, glycosylated cytokine hormone composed of four alpha helical bundles. The protein is found in the plasma and regulates red cell production by promoting erythroid differentiation and initiating hemoglobin synthesis. This protein also has neuroprotective activity against a variety of potential brain injuries and antiapoptotic functions in several tissue types. It is produced by kidney or liver of adult mammals and by liver of fetal or neonatal mammals.Synonyms: Epoetin
- Gen-ID
- 2056
- NCBI Accession
- NP_000790
- UniProt
- P01588
- Pathways
- JAK-STAT Signalweg, Hormone Activity, Negative Regulation of intrinsic apoptotic Signaling, Negative Regulation of Transporter Activity
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