This antibody reacts with Pancreatic Polypeptide. It stains the periphery of islets, exocrine pancreatic parenchyma, and the epithelium of small and medium sized ducts and acinar cells. Cellular Localization: Cytoplasmic.
Aufreinigung
Purified
Immunogen
Synthetic Human Pancreatic Polypeptide conjugated to Keyhole Limpet Hemocyanin.
PPY
Reaktivität: Human
WB, ICC, IF
Wirt: Maus
Monoclonal
GT327
unconjugated
Applikationshinweise
Immunohistochemistry on Frozen and Paraffin Embedded Sections: diluted of 1/25-1/50 inan ABC method (30 minutes at room temperature)Recommended Positive Control: Pancreas. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Handhabung
Avoid repeated freezing and thawing.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store the antibody undiluted at 2-8 °C for one mounth or (in aliquots) at -20 °C for longer.
Pancreatic hormone is synthesized in pancreatic islets of Langerhans and acts as a regulator of pancreatic and gastrointestinal functions and may be important in the regulation of food intake. Plasma levels of this hormone have been shown to be reduced in conditions associated with increased food intake and elevated in anorexia nervosa. In addition, infusion of this hormone in obese rodents has shown to decrease weight gain.Synonyms: Obinepitide, PNP, PPY, Pancreatic polypeptide