This antibody reacts with a 145 kDa protein. This antibody can be used in the identification of gastrointestinal stromal tumors. Cellular Localization: Cell membrane, cytoplasm.
Aufreinigung
Purified
Immunogen
A synthetic peptide from c-terminus of Human CD117/c-kit protein.
Immunohistochemistry on Paraffin Embedded Sections: Use 1/50-1/100 diluted antibody inan ABC method (30 minutes at room temperature). Recommended Positive Control: Tonsil. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
C-kits is expressed in many tissues and cells. c-kits is involved in the development of several lineages of stem cells, such as germ cells, neural crest derived melanocytes and hematopoietic precursor cells. This antibody can be used in the identification of gastrointestinal stromal tumors.Synonyms: KIT, Mast/stem cell growth factor receptor, Proto-Oncogene Tyrosine-Protein Kinase, SCFR