LAG3 Antikörper (N-Term) (Atto 488)
-
- Target Alle LAG3 Antikörper anzeigen
- LAG3 (Lymphocyte-Activation Gene 3 (LAG3))
-
Bindungsspezifität
- N-Term
-
Reaktivität
- Human
-
Wirt
- Maus
-
Klonalität
- Monoklonal
-
Konjugat
- Dieser LAG3 Antikörper ist konjugiert mit Atto 488
-
Applikation
- Flow Cytometry (FACS), Immunocytochemistry (ICC)
- Spezifität
- Recognizes human LAG-3.
- Kreuzreaktivität
- Human
- Reinheit
- >95 % (SDS-PAGE)
- Immunogen
- Synthetic peptide corresponding to 30 aa in the N-terminus of human LAG-3.
- Klon
- 17B4
- Isotyp
- IgG1
- Top Product
- Discover our top product LAG3 Primärantikörper
-
-
- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Kommentare
-
New ATTO-fluorescent antibodies show increased photostability, outstanding brightness and intense signals. ATTO dyes are thermally stable, resistant to environmental changes and show no significant isomerization. ATTO 488 shows bright green fluorescence (lambdaabs (max): 501nm, lambdaem (max): 523nm, epsilonmax: 90'000).
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- In PBS containing 0.02 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C
- Informationen zur Lagerung
-
Short Term Storage: +4°C
Long Term Storage: +4°C
Keep conjugated formats at +4°C. Stable for at least 1 year after receipt when stored at +4°C. - Haltbarkeit
- 12 months
-
- Target
- LAG3 (Lymphocyte-Activation Gene 3 (LAG3))
- Andere Bezeichnung
- LAG-3 (LAG3 Produkte)
- Synonyme
- CD223 antikoerper, LAG-3 antikoerper, Ly66 antikoerper, lymphocyte activating 3 antikoerper, lymphocyte-activation gene 3 antikoerper, LAG3 antikoerper, Lag3 antikoerper
- Hintergrund
- Lymphocyte activation gene 3 (LAG-3, CD223) plays an important role in negatively regulating T cell proliferation, function and homeostasis. It is required for maximal natural and induced regulatory T cell (Treg) function. LAG-3 is closely related to the T cell co-receptor CD4 and binds to MHC class II molecules but with a significantly higher affinity than CD4.
- UniProt
- P18627
- Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
-