IGF-like family receptor 1 (IGFLR1) (AA 23-154) Antikörper

Produktnummer ABIN1169119

Produktdetails

Target: IGF-like family receptor 1 (IGFLR1)

Bindungsspezifität: AA 23-154

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS)

Spezifität: Recognizes human IGFLR1.

Kreuzreaktivität: Human

Keine Kreuzreaktivität: Maus

Kreuzreaktivität (Details): Does not recognize mouse IGFLR1.

Immunogen: Recombinant human IGFLR1 (aa 23-154).

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: In PBS containing 10 % glycerol and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 1 year after receipt when stored at -20°C.

Haltbarkeit: 12 months

Antigendetails

Target: IGF-like family receptor 1 (IGFLR1)

Andere Bezeichnung: IGFLR1 (IGFLR1 Produkte)

Hintergrund: Insulin-growth factor-like gene family is a new family of proteins consisting of four proteins in humans (IGFL1 to 4) and one in mice (mIGFL). mIGFL is expressed in normal skin in mice and further upregulated during inflammation responses in skin or after skin wounding. In human only IGFL1 expression is increased in psoriatic skin samples. Mouse IGFL and human IGFL1 and 3 interact with specificity and high affinity to a novel receptor named IGF-like family receptor 1 (formerly TMEM-149). Analysis of the amino acid sequence of IGFLR1 indicated that this receptor is likely a novel member of the TNFR family. IGFLR1 is expressed most abundantly on mouse T cells, suggesting that mIGFL and IGFL1 produced in the skin may potentially exert regulatory functions on T cell responses.

UniProt: Q9H665