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IL-33 Antikörper
IL33
Reaktivität: Human
WB, ELISA, IHC, IP, Func
Wirt: Maus
Monoclonal
IL33305B
unconjugated
Produktnummer ABIN1169175
Produktdetails anti-IL-33 Antikörper
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Target
Alle IL-33 (IL33) Antikörper anzeigen
IL-33 (IL33)
(Interleukin 33 (IL33))
Reaktivität
Alle Reaktivitäten für IL-33 Antikörper
Human
Wirt
Alle Wirte für IL-33 Antikörper
Maus
Klonalität
Alle Klonalitäten für IL-33 Antikörper
Monoklonal
Konjugat
Alle Konjugate für IL-33 Antikörper
Dieser IL-33 Antikörper ist unkonjugiert
Applikation
Alle Applikationen für IL-33 Antikörper
Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP), Functional Studies (Func)
Spezifität
Recognizes human IL-33.
Kreuzreaktivität
Human
Keine Kreuzreaktivität
Maus
Kreuzreaktivität (Details)
Does not cross-react with mouse IL-33.
Sterilität
0.2 μm filtered
Immunogen
Recombinant human IL-33.
Klon
IL33305B
Isotyp
IgG2a
Top Product
Discover our top product IL33 Primärantikörper
Alternativen
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Anwendungsinformationen
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Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Format
Liquid
Konzentration
Lot specific
Buffer
0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives.
Konservierungsmittel
Without preservative
Lagerung
4 °C,-20 °C
Informationen zur Lagerung
Short Term Storage: +4°C Long Term Storage: -20°C Stable for at least 1 year after receipt when stored at -20°C.
Haltbarkeit
12 months
Referenzen für anti-IL-33 Antikörper (ABIN1169175)
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Pace, Di Sano, Sciarrino, Scafidi, Ferraro, Chiappara, Siena, Gangemi, Vitulo, Giarratano, Gjomarkaj : "Cigarette smoke alters IL-33 expression and release in airway epithelial cells. " in: Biochimica et biophysica acta , Vol. 1842 , Issue 9 , pp. 1630-7 , (2014 ) (PubMed ).
Details zu IL-33
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Target
IL-33 (IL33)
(Interleukin 33 (IL33))
Andere Bezeichnung
IL-33 (IL33 Produkte )
Synonyme
IL33 antikoerper, C9orf26 antikoerper, DVS27 antikoerper, IL1F11 antikoerper, NF-HEV antikoerper, NFEHEV antikoerper, RP11-575C20.2 antikoerper, 9230117N10Rik antikoerper, Il-33 antikoerper, Il1f11 antikoerper, RGD1311155 antikoerper, interleukin 33 antikoerper, IL33 antikoerper, Il33 antikoerper
Hintergrund
Interleukin-33 (IL-33, HF-NEV, IL-1F11), a member of the IL-1 family of cytokines, is expressed by many cell types following pro-inflammatory stimulation and is thought to be released on cell lysis. The 30 kDa human IL33 is converted by CASP1 to a 18 kDa protein. IL33 binds to and signals through ST2 (IL1R1) and its stimulation recruits MYD88, IRAK, IRAK4, and TRAF6, followed by phosphorylation of ERK1 (MAPK3)/ERK2 (MAPK1), p38(MAPK14), and JNK. The ability of IL-33 to target numerous immune cell types, like Th2-like cells, mast cells, and B1 cells, and to induce cytokine and chemokine production underlines its potential in influencing the outcome of a wide range of diseases, such as arthritis, asthma, atopic allergy & anaphylaxis, cardiovascular disease/atherosclerosis, nervous system diseases, and sepsis.
UniProt
O95760
Pathways
Production of Molecular Mediator of Immune Response
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