IL-37 Antikörper

Produktnummer ABIN1169178

Produktdetails anti-IL-37 Antikörper

Target: IL-37 (IL37) (Interleukin 37 (IL37))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IL-37 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP)

Spezifität: Recognizes human IL-37. Detects a band of ~30 kDa by Western blot.

Kreuzreaktivität: Human

Sterilität: 0.2 μm filtered

Immunogen: Recombinant human IL-37.

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives.

Konservierungsmittel: Without preservative

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 6 months after receipt when stored at -20°C.

Haltbarkeit: 6 months

Details zu IL-37

Target: IL-37 (IL37) (Interleukin 37 (IL37))

Andere Bezeichnung: IL-37 (IL37 Produkte)

Synonyme: FIL1 antikoerper, FIL1(ZETA) antikoerper, FIL1Z antikoerper, IL-1F7 antikoerper, IL-1H antikoerper, IL-1H4 antikoerper, IL-1RP1 antikoerper, IL-37 antikoerper, IL1F7 antikoerper, IL1H4 antikoerper, IL1RP1 antikoerper, interleukin 37 antikoerper, IL37 antikoerper

Hintergrund: IL-37 (IL-1F7, IL-1H4) is an IL-1 family member that is expressed only in certain types of human organs and cells such as heart, thymus, testis, kidney, mononuclear cells (PBMCs) and dendritic cells. IL-37 is an inhibitor of innate immunity with anti-inflammatory properties. It binds to the interleukin-18 receptor (IL-18R) and its co-receptor SIGIRR. IL-37 is secreted as a full-length and as a processed form starting from amino acid Val46. It plays an important role as a link between innate and adaptive immunity and acts as an inhibitor of autoimmune diseases and tumor growth. IL-37 also inhibited Lipopolysaccharide (LPS)-induced immunological reaction and LPS-induced osteoclast formation and bone resorption.

UniProt: Q9NZH6