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TICAM2 Antikörper (AA 2-29)

TICAM2 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN1169199
  • Target Alle TICAM2 Antikörper anzeigen
    TICAM2 (Toll-Like Receptor Adaptor Molecule 2 (TICAM2))
    Bindungsspezifität
    • 8
    • 8
    • 6
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 2-29
    Reaktivität
    • 50
    • 17
    • 15
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 47
    • 2
    • 1
    • 1
    Kaninchen
    Klonalität
    • 51
    • 1
    Polyklonal
    Konjugat
    • 30
    • 5
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser TICAM2 Antikörper ist unkonjugiert
    Applikation
    • 43
    • 24
    • 7
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Spezifität
    Recognizes human TRAM.
    Kreuzreaktivität
    Human
    Immunogen
    Synthetic peptide corresponding to aa 2-29 (G2IGKSKINSCPLSLSWGKRHSVDTSPGY29) of human TRAM.
    Top Product
    Discover our top product TICAM2 Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Neat serum containing 0.02 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Short Term Storage: +4°C
    Long Term Storage: -20°C
    Stable for at least 1 year after receipt when stored at -20°C.
    Haltbarkeit
    12 months
  • Aksoy, Albarani, Nguyen, Laes, Ruelle, De Wit, Willems, Goldman, Goriely: "Interferon regulatory factor 3-dependent responses to lipopolysaccharide are selectively blunted in cord blood cells." in: Blood, Vol. 109, Issue 7, pp. 2887-93, (2007) (PubMed).

  • Target
    TICAM2 (Toll-Like Receptor Adaptor Molecule 2 (TICAM2))
    Andere Bezeichnung
    TRAM (TICAM2 Produkte)
    Synonyme
    MyD88-4 antikoerper, TICAM-2 antikoerper, TIRAP3 antikoerper, TIRP antikoerper, TRAM antikoerper, B430113A10 antikoerper, Tirp antikoerper, Trif antikoerper, toll like receptor adaptor molecule 2 antikoerper, toll-like receptor adaptor molecule 2 antikoerper, TICAM2 antikoerper, Ticam2 antikoerper
    Hintergrund
    TRAM functions in LPS-TLR4 signaling to regulate the MYD88-independent pathway during the innate immune response to LPS. It is also involved in IL-1-triggered NF-kappaB activation, functioning upstream of IRAK1, IRAK2, TRAF6 and IKBKB. TRAM physically bridges TLR4 and TICAM-1 and functionally transmits LPS-TRL4 signal to TICAM-1. It is expressed in spleen, prostate, testis, uterus, small intestine, colon, peripheral blood leukocytes, heart, placenta, lung, liver, skeletal muscle and pancreas.
    UniProt
    Q86XR7
    Pathways
    TLR Signalweg, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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