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ARHGEF7 Antikörper

ARHGEF7 Reaktivität: Human, Ratte, Maus WB, ELISA, ICC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN1169227
  • Target Alle ARHGEF7 Antikörper anzeigen
    ARHGEF7 (rho Guanine Nucleotide Exchange Factor (GEF) 7 (ARHGEF7))
    Reaktivität
    • 44
    • 17
    • 17
    • 1
    • 1
    Human, Ratte, Maus
    Wirt
    • 45
    • 3
    Kaninchen
    Klonalität
    • 46
    • 2
    Polyklonal
    Konjugat
    • 19
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser ARHGEF7 Antikörper ist unkonjugiert
    Applikation
    • 23
    • 21
    • 13
    • 13
    • 7
    • 7
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunocytochemistry (ICC)
    Spezifität
    Recognizes the multiple splice variants of human, mouse and rat beta-Pix a, b, bL, c and d-isoforms.
    Kreuzreaktivität
    Human, Maus, Ratte (Rattus)
    Kreuzreaktivität (Details)
    Cross-reacts with human and rat beta-Pix.
    Sterilität
    0.2 μm filtered
    Immunogen
    Recombinant beta-Pix SH3 domain.
    Top Product
    Discover our top product ARHGEF7 Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives.
    Konservierungsmittel
    Without preservative
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Short Term Storage: +4°C
    Long Term Storage: -20°C
    Stable for at least 6 months after receipt when stored at -20°C.
    Haltbarkeit
    6 months
  • Oh, Yoo, Jo, Song, Kim, Park: "Cloning of a SH3 domain-containing proline-rich protein, p85SPR, and its localization in focal adhesion." in: Biochemical and biophysical research communications, Vol. 235, Issue 3, pp. 794-8, (1997) (PubMed).

  • Target
    ARHGEF7 (rho Guanine Nucleotide Exchange Factor (GEF) 7 (ARHGEF7))
    Andere Bezeichnung
    beta-Pix (ARHGEF7 Produkte)
    Hintergrund
    Beta-PIX acts as a RAC1 guanine nucleotide exchange factor (GEF) and can induce membrane ruffling. It interacts with PAK kinases through the SH3 domain. It may function as a positive regulator of apoptosis and is involved in cell migration. It is expressed with high levels in the central nervous system.
    UniProt
    Q9ES28
    Pathways
    EGFR Signaling Pathway, Neurotrophin Signalübertragung, EGFR Downregulation
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