ARHGEF7 Antikörper

Produktnummer ABIN1169227

Produktdetails anti-ARHGEF7 Antikörper

Target: ARHGEF7 (rho Guanine Nucleotide Exchange Factor (GEF) 7 (ARHGEF7))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ARHGEF7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunocytochemistry (ICC)

Spezifität: Recognizes the multiple splice variants of human, mouse and rat beta-Pix a, b, bL, c and d-isoforms.

Kreuzreaktivität: Human, Maus, Ratte (Rattus)

Kreuzreaktivität (Details): Cross-reacts with human and rat beta-Pix.

Sterilität: 0.2 μm filtered

Immunogen: Recombinant beta-Pix SH3 domain.

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives.

Konservierungsmittel: Without preservative

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 6 months after receipt when stored at -20°C.

Haltbarkeit: 6 months

Referenzen für anti-ARHGEF7 Antikörper (ABIN1169227)

Oh, Yoo, Jo, Song, Kim, Park: "Cloning of a SH3 domain-containing proline-rich protein, p85SPR, and its localization in focal adhesion." in: Biochemical and biophysical research communications, Vol. 235, Issue 3, pp. 794-8, (1997) (PubMed).

Details zu ARHGEF7

Target: ARHGEF7 (rho Guanine Nucleotide Exchange Factor (GEF) 7 (ARHGEF7))

Andere Bezeichnung: beta-Pix (ARHGEF7 Produkte)

Synonyme: BETA-PIX antikoerper, COOL-1 antikoerper, COOL1 antikoerper, Nbla10314 antikoerper, P50 antikoerper, P50BP antikoerper, P85 antikoerper, P85COOL1 antikoerper, P85SPR antikoerper, PAK3 antikoerper, PIXB antikoerper, cool1 antikoerper, p50 antikoerper, p85 antikoerper, pak3 antikoerper, pixb antikoerper, ARHGEF7 antikoerper, P85spr antikoerper, Pak3bp antikoerper, Cool antikoerper, PIX antikoerper, betaPix antikoerper, betaPix-b antikoerper, betaPix-c antikoerper, cool-1 antikoerper, mKIAA0142 antikoerper, p85Cool1 antikoerper, p85SPR antikoerper, arhgef7 antikoerper, bbh antikoerper, bpix antikoerper, im:7142367 antikoerper, wu:fc35h08 antikoerper, zgc:101775 antikoerper, Rho guanine nucleotide exchange factor 7 antikoerper, Rho guanine nucleotide exchange factor 7 S homeolog antikoerper, ankyrin repeat domain 10 antikoerper, Rho guanine nucleotide exchange factor (GEF7) antikoerper, Rho guanine nucleotide exchange factor (GEF) 7b antikoerper, ARHGEF7 antikoerper, arhgef7.S antikoerper, arhgef7 antikoerper, ANKRD10 antikoerper, Arhgef7 antikoerper, arhgef7b antikoerper

Hintergrund: Beta-PIX acts as a RAC1 guanine nucleotide exchange factor (GEF) and can induce membrane ruffling. It interacts with PAK kinases through the SH3 domain. It may function as a positive regulator of apoptosis and is involved in cell migration. It is expressed with high levels in the central nervous system.

UniProt: Q9ES28

Pathways: EGFR Signaling Pathway, Neurotrophin Signalübertragung, EGFR Downregulation