MEFV Antikörper (AA 2-29)
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- Target Alle MEFV Antikörper anzeigen
- MEFV (Mediterranean Fever (MEFV))
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Bindungsspezifität
- AA 2-29
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser MEFV Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunoprecipitation (IP)
- Spezifität
- Recognizes human pyrin.
- Kreuzreaktivität
- Human
- Immunogen
- Synthetic peptide corresponding to aa 2-29 (A2KTPSDHLLSTLEELVPYDFEKFKFKLQ29) of human pyrin.
- Top Product
- Discover our top product MEFV Primärantikörper
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- In PBS containing 10 % glycerol and 0.02 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
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Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 1 year after receipt when stored at -20°C. - Haltbarkeit
- 12 months
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The SPRY domain of Pyrin, mutated in familial Mediterranean fever patients, interacts with inflammasome components and inhibits proIL-1beta processing." in: Cell death and differentiation, Vol. 14, Issue 8, pp. 1457-66, (2007) (PubMed).
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The SPRY domain of Pyrin, mutated in familial Mediterranean fever patients, interacts with inflammasome components and inhibits proIL-1beta processing." in: Cell death and differentiation, Vol. 14, Issue 8, pp. 1457-66, (2007) (PubMed).
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- Target
- MEFV (Mediterranean Fever (MEFV))
- Andere Bezeichnung
- Pyrin (MEFV Produkte)
- Synonyme
- pyrin antikoerper, MEFV antikoerper, FMF antikoerper, MEF antikoerper, TRIM20 antikoerper, rfp domain antikoerper, MEFV, pyrin innate immunity regulator antikoerper, Mediterranean fever antikoerper, MEFV antikoerper, Mefv antikoerper
- Hintergrund
- Pyrin regulates inflammation by interacting with the cytoskeleton. Pyrin may direct the migration of white blood cells to sites of inflammation and stop or slow the inflammatory response when it is no longer needed. Defects in pyrin are the cause for Mediterranean fever.
- UniProt
- O15553
- Pathways
- Positive Regulation of Endopeptidase Activity
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