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Caspase 1 p20 Antikörper (Biotin)

Reaktivität: Maus WB, IP, IHC Wirt: Maus Monoclonal Casper-1 Biotin
Produktnummer ABIN1169383
  • Target Alle Caspase 1 p20 Produkte
    Caspase 1 p20
    Reaktivität
    • 51
    • 33
    • 32
    Maus
    Wirt
    • 49
    • 3
    Maus
    Klonalität
    • 49
    • 3
    Monoklonal
    Konjugat
    • 6
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    Dieser Caspase 1 p20 Antikörper ist konjugiert mit Biotin
    Applikation
    • 42
    • 36
    • 26
    • 26
    • 10
    • 9
    • 6
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC)
    Spezifität
    Recognizes endogenous full-length and activated (p20 fragment) mouse caspase-1.
    Kreuzreaktivität
    Maus
    Aufreinigung
    Purified from concentrated hybridoma tissue culture supernatant.
    Reinheit
    >95 % (SDS-PAGE)
    Immunogen
    Recombinant mouse caspase-1.
    Klon
    Casper-1
    Isotyp
    IgG1
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    In PBS containing 0.02 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Short Term Storage: +4°C
    Long Term Storage: -20°C
    Stable for at least 1 year after receipt when stored at -20°C.
    Haltbarkeit
    12 months
  • Carpentier, Ni, Duggan, James, Cookson, Hamerman: "The signaling adaptor BCAP inhibits NLRP3 and NLRC4 inflammasome activation in macrophages through interactions with Flightless-1." in: Science signaling, Vol. 12, Issue 581, (2020) (PubMed).

  • Target
    Caspase 1 p20
    Andere Bezeichnung
    Caspase-1 p20 (Caspase 1 p20 Produkte)
    Hintergrund
    Caspase-1 is the best-described inflammatory caspase. It processes the cytokines interleukin-1beta (IL-1beta) and IL-18 and induces pyroptotic cell death. Caspase-1 is activated by multiprotein complexes called Inflammasomes in response to numerous stimuli that are detected through distinct inflammasomes. NLRC4 responds to cytosolic flagellin, murine NLRP1b responds to anthrax lethal toxin, AIM2 responds to cytosolic DNA and NLRP3 responds to a variety of agonists including crystals.
    UniProt
    P29452
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