Caspase 1 p20 Antikörper (Biotin)
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- Target Alle Caspase 1 p20 Produkte
- Caspase 1 p20
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Reaktivität
- Maus
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser Caspase 1 p20 Antikörper ist konjugiert mit Biotin
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Applikation
- Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC)
- Spezifität
- Recognizes endogenous full-length and activated (p20 fragment) mouse caspase-1.
- Kreuzreaktivität
- Maus
- Aufreinigung
- Purified from concentrated hybridoma tissue culture supernatant.
- Reinheit
- >95 % (SDS-PAGE)
- Immunogen
- Recombinant mouse caspase-1.
- Klon
- Casper-1
- Isotyp
- IgG1
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- In PBS containing 0.02 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
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Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 1 year after receipt when stored at -20°C. - Haltbarkeit
- 12 months
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The signaling adaptor BCAP inhibits NLRP3 and NLRC4 inflammasome activation in macrophages through interactions with Flightless-1." in: Science signaling, Vol. 12, Issue 581, (2020) (PubMed).
: "
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The signaling adaptor BCAP inhibits NLRP3 and NLRC4 inflammasome activation in macrophages through interactions with Flightless-1." in: Science signaling, Vol. 12, Issue 581, (2020) (PubMed).
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- Target
- Caspase 1 p20
- Andere Bezeichnung
- Caspase-1 p20 (Caspase 1 p20 Produkte)
- Hintergrund
- Caspase-1 is the best-described inflammatory caspase. It processes the cytokines interleukin-1beta (IL-1beta) and IL-18 and induces pyroptotic cell death. Caspase-1 is activated by multiprotein complexes called Inflammasomes in response to numerous stimuli that are detected through distinct inflammasomes. NLRC4 responds to cytosolic flagellin, murine NLRP1b responds to anthrax lethal toxin, AIM2 responds to cytosolic DNA and NLRP3 responds to a variety of agonists including crystals.
- UniProt
- P29452
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