Neutrophils Antikörper
Reaktivität: Maus
FACS, IHC, Func, ICC
Wirt: Ratte
Monoclonal
Nimp-R14
unconjugated
(8 Referenzen)-
- Target Alle Neutrophils Produkte
- Neutrophils
- Reaktivität
- Maus
-
Wirt
- Ratte
-
Klonalität
- Monoklonal
-
Konjugat
- Dieser Neutrophils Antikörper ist unkonjugiert
-
Applikation
- Flow Cytometry (FACS), Immunohistochemistry (IHC), Functional Studies (Func), Immunocytochemistry (ICC)
- Spezifität
- Recognizes mouse neutrophils (surface protein mouse Ly-6G) and may recognize Ly-6Chigh cells (inflammatory monocytes).
- Kreuzreaktivität
- Maus
- Aufreinigung
- Purified from concentrated hybridoma tissue culture supernatant.
- Reinheit
- >95 % (SDS-PAGE)
- Endotoxin-Niveau
- <0.1EU/μg purified protein (LAL test, Lonza).
- Immunogen
- Purified mouse BALB/c neutrophils.
- Klon
- Nimp-R14
- Isotyp
- IgG2b
-
anti-Neutrophils antibody (PE)
Reaktivität: Maus FACS Wirt: Ratte Monoclonal 07-04-14 PE
-
- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Kommentare
-
Negative control: AG-35B-0011 http://www.adipogen.com/ag-35b-0011/rat-igg2b-isotype-control.html
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- In PBS containing 10 % glycerol and 0.02 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
-
Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 1 year after receipt when stored at -20°C. - Haltbarkeit
- 12 months
-
-
: "Intraperitoneal neutrophils activated by KRAS-induced ovarian cancer exert antitumor effects by modulating adaptive immunity." in: International journal of oncology, Vol. 53, Issue 4, pp. 1580-1590, (2018) (PubMed).
: "Rapid recruitment of inflammatory monocytes is independent of neutrophil migration." in: Blood, Vol. 102, Issue 1, pp. 328-35, (2003) (PubMed).
: "Complement factor C5a mediates renal ischemia-reperfusion injury independent from neutrophils." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 170, Issue 7, pp. 3883-9, (2003) (PubMed).
: "An immunomodulatory function for neutrophils during the induction of a CD4+ Th2 response in BALB/c mice infected with Leishmania major." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 165, Issue 5, pp. 2628-36, (2000) (PubMed).
: "A new mechanism for IL-5-dependent helminth control: neutrophil accumulation and neutrophil-mediated worm encapsulation in murine filariasis are abolished in the absence of IL-5." in: International immunology, Vol. 12, Issue 6, pp. 899-908, (2000) (PubMed).
: "Adenoviral vector-mediated overexpression of IL-4 in the knee joint of mice with collagen-induced arthritis prevents cartilage destruction." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 163, Issue 8, pp. 4546-56, (1999) (PubMed).
: "Monocytes/macrophages rather than PMN are involved in early cartilage degradation in cationic immune complex arthritis in mice." in: Journal of leukocyte biology, Vol. 61, Issue 3, pp. 267-78, (1997) (PubMed).
: "Differentiation antigens on mouse eosinophils and neutrophils identified by monoclonal antibodies." in: British journal of haematology, Vol. 57, Issue 3, pp. 489-94, (1984) (PubMed).
-
: "Intraperitoneal neutrophils activated by KRAS-induced ovarian cancer exert antitumor effects by modulating adaptive immunity." in: International journal of oncology, Vol. 53, Issue 4, pp. 1580-1590, (2018) (PubMed).
-
- Target
- Neutrophils
- Abstract
- Neutrophils Produkte
- Hintergrund
- Neutrophils are key components of the inflammatory response and as such contribute to the killing of microorganisms. In addition, recent evidence suggests their involvement in the development of the immune response. The Nimp-R14 mAb displays features of an optimal reagent allowing the selective depletion of mouse neutrophils in vivo.
- UniProt
- P35461
-
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