Rekombinanter IL1R2 Antikörper (Extracellular Domain)
-
- Target Alle IL1R2 Antikörper anzeigen
- IL1R2 (Interleukin 1 Receptor, Type II (IL1R2))
- Antikörpertyp
- Recombinant Antibody
-
Bindungsspezifität
- Extracellular Domain
-
Reaktivität
- Maus
-
Wirt
- Maus
-
Klonalität
- Monoklonal
-
Konjugat
- Dieser IL1R2 Antikörper ist unkonjugiert
-
Applikation
- ELISA, Flow Cytometry (FACS)
- Spezifität
- Recognizes mouse IL-1R2.
- Kreuzreaktivität
- Maus
- Aufreinigung
- Purified from HEK 293 cell culture supernatant.
- Reinheit
- >95 % (SDS-PAGE)
- Endotoxin-Niveau
- <0.01EU/μg purified protein (LAL-test, Lonza).
- Immunogen
- Recombinant mouse IL-1R2 (extracellular domain).
- Klon
- Praxy-1-1
- Isotyp
- IgG2b
- Top Product
- Discover our top product IL1R2 Primärantikörper
-
-
- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Kommentare
-
IL-1R2 (mouse) monoclonal antibody (recombinant) (Praxy-1-1) is composed of human variable regions (VH and VL) (lambda-chain) of immunoglobulin fused to the mouse IgG2b Fc domain.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- In PBS containing 10 % glycerol and 0.02 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
-
Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 1 month after receipt when stored at +4°C. Stable for at least 1 year after receipt when stored at -20°C. - Haltbarkeit
- 12 months
-
- Target
- IL1R2 (Interleukin 1 Receptor, Type II (IL1R2))
- Andere Bezeichnung
- IL-1R2 (IL1R2 Produkte)
- Synonyme
- CD121b antikoerper, CDw121b antikoerper, IL-1R-2 antikoerper, IL-1RT-2 antikoerper, IL-1RT2 antikoerper, IL1R2c antikoerper, IL1RB antikoerper, Il1r-2 antikoerper, IL-1R2 antikoerper, interleukin 1 receptor type 2 antikoerper, interleukin 1 receptor, type II antikoerper, interleukin-like antikoerper, IL1R2 antikoerper, Il1r2 antikoerper, KK34 antikoerper
- Hintergrund
- The inflammatory actions of IL-1alpha and beta depend on their interaction with its receptor, IL-1R1, and can be negatively controlled by several inhibitors such as IL-1Ra, IL-1R type 2 (IL-1R2), SIGIRR and the soluble form of IL-1 receptor accessory protein (IL-1RAcP). IL-1R2 neutralizes IL-1 either as a surface decoy receptor or in a cleaved and secreted form. IL-1R2 is expressed on B cells, on neutrophils and on in vitro expanded human Tregs.
- UniProt
- P27931
- Pathways
- NF-kappaB Signalweg
-