Aktivieren Sie Javascript in Ihrem Browser, um unsere Webseite optimal zu nutzen.

ACE2 Antikörper

Name: ACE2 Antikörper
Brand: antibodies-online
SKU: ABIN1169449
Price: 440.38 EUR
Availability: InStock

ACE2 Reaktivität: Human WB, ELISA, FACS Wirt: Maus Monoclonal AC18F unconjugated

Western blot analysis using anti-ACE2 (human), mAb (AC18F) at 1: 2,000 dilution. (ACE2 Antikörper)

Black histograms represent the background staining of 293T parental cells and gray-filled histograms represents background staining of 293T-ACE2 cells. (ACE2 Antikörper)

FACS

ACE2 expression assessed by western blot in U2OS-ACE2 GFP-split cells expressing or not IFITM1. (ACE2 Antikörper)

Immunostaining of corneal tissue from postmortem donors with and without COVID-19-positive PCR for spike protein from SARS-CoV-2 (red) and ACE2 (green) indicated with white arrows, with nuclei in blue. (ACE2 Antikörper)

ISt

5 Abbildungen

(4 Referenzen)

Produktnummer ABIN1169449

Datenblatt (PDF)

Target Alle ACE2 Antikörper anzeigen

ACE2 (Angiotensin I Converting Enzyme 2 (ACE2))
Reaktivität
133

52

46

5

4

1

1

1

1

1

1
Human
Wirt
121

18

6
Maus
Passende Sekundärantikörper
Klonalität
111

34
Monoklonal
Konjugat
73

15

10

8

5

4

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Dieser ACE2 Antikörper ist unkonjugiert
Applikation
113

63

48

34

30

19

17

10

10

10

9

6

3

1

1

1
Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Spezifität

Recognizes human ACE2.

Kreuzreaktivität

Human

Sterilität

0.2 μm filtered

Immunogen

Recombinant human ACE2.

Klon

AC18F

Isotyp

IgG1
anti-Angiotensin I Converting Enzyme 2 (ACE2) (AA 601-700) antibody
ACE2 Reaktivität: Human, Maus, Ratte WB, ELISA, FACS, IHC (p), ICC, IF (cc), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated

anti-Angiotensin I Converting Enzyme 2 (ACE2) (AA 18-250) antibody
ACE2 Reaktivität: Human WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated

anti-Angiotensin I Converting Enzyme 2 (ACE2) (AA 93-464) antibody
ACE2 Reaktivität: Maus WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-Angiotensin I Converting Enzyme 2 (ACE2) (AA 392-739) antibody
ACE2 Reaktivität: Ratte WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-Angiotensin I Converting Enzyme 2 (ACE2) (AA 773-805), (C-Term) antibody
ACE2 Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal RB4819 unconjugated

anti-Angiotensin I Converting Enzyme 2 (ACE2) (N-Term) antibody
Verified ACE2 Reaktivität: Human WB, ELISA, IHC, FACS Wirt: Ziege Polyclonal unconjugated

anti-Angiotensin I Converting Enzyme 2 (ACE2) (AA 59-90) antibody
ACE2 Reaktivität: Human WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated

anti-Angiotensin I Converting Enzyme 2 (ACE2) (AA 140-172) antibody
ACE2 Reaktivität: Human WB, ELISA, IHC, FACS Wirt: Kaninchen Polyclonal unconjugated

anti-Angiotensin I Converting Enzyme 2 (ACE2) (AA 395-638) antibody
ACE2 Reaktivität: Human ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated

anti-Angiotensin I Converting Enzyme 2 (ACE2) (AA 59-90), (N-Term) antibody
ACE2 Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal RB4811-4812 unconjugated

Applikationshinweise

Optimal working dilution should be determined by the investigator.

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Konzentration

Lot specific

Buffer

0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives.

Konservierungsmittel

Without preservative

Lagerung

4 °C,-20 °C

Informationen zur Lagerung

Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 1 year after receipt when stored at -20°C.

Haltbarkeit

12 months
Chaouat, Achdout, Kol, Berhani, Roi, Vitner, Melamed, Politi, Zahavy, Brizic, Lenac Rovis, Alfi, Wolf, Jonjic, Israely, Mandelboim: "SARS-CoV-2 receptor binding domain fusion protein efficiently neutralizes virus infection." in: PLoS pathogens, Vol. 17, Issue 12, pp. e1010175, (2022) (PubMed).

Chaouat, Brizic, Kucan Brlic, Atari, Kliker, Alfi, Mandelboim, Wolf, Tafish, Kol, Jonjic, Mandelboim: "Anti-human ACE2 antibody neutralizes and inhibits virus production of SARS-CoV-2 variants of concern." in: iScience, Vol. 25, Issue 9, pp. 104935, (2022) (PubMed).

Buchrieser, Dufloo, Hubert, Monel, Planas, Rajah, Planchais, Porrot, Guivel-Benhassine, Van der Werf, Casartelli, Mouquet, Bruel, Schwartz: "Syncytia formation by SARS-CoV-2-infected cells." in: The EMBO journal, pp. e106267, (2020) (PubMed).

Zulli, Rai, Buxton, Burrell, Hare: "Co-localization of angiotensin-converting enzyme 2-, octomer-4- and CD34-positive cells in rabbit atherosclerotic plaques." in: Experimental physiology, Vol. 93, Issue 5, pp. 564-9, (2008) (PubMed).
Target

ACE2 (Angiotensin I Converting Enzyme 2 (ACE2))

Andere Bezeichnung

ACE2 (ACE2 Produkte)

Synonyme

ACE1 antikoerper, CD143 antikoerper, DCP antikoerper, DCP1 antikoerper, ICH antikoerper, MVCD3 antikoerper, ACEH antikoerper, 2010305L05Rik antikoerper, zgc:92514 antikoerper, angiotensin I converting enzyme antikoerper, angiotensin I converting enzyme 2 antikoerper, angiotensin I converting enzyme (peptidyl-dipeptidase A) 2 antikoerper, ACE antikoerper, ACE2 antikoerper, Ace2 antikoerper, ace2 antikoerper

Hintergrund

ACE2 has direct effects on cardiac functions. It is expressed predominantly in vascular endothelial cells of the heart and kidney. ACE2 converts angiotensin I to angiotensin 1-9. ACE2 was also identified as a functional receptor for SARS coronavirus.

UniProt

Q9BYF1

Pathways

ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour