CD4 Antikörper
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- Target Alle CD4 Antikörper anzeigen
- CD4
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Reaktivität
- Maus
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Wirt
- Ratte
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Klonalität
- Monoklonal
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Konjugat
- Dieser CD4 Antikörper ist unkonjugiert
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Applikation
- Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Functional Studies (Func)
- Spezifität
- This antibody recognises the CD4 cell surface antigen, expressed by a subset of T lymphocytes. This clone exhibits depleting activity when used in vivo.
- Aufreinigung
- Affinity chromatography on Protein G
- Endotoxin-Niveau
- Low Endotoxin
- Klon
- YTS191-1
- Isotyp
- IgG2b
- Top Product
- Discover our top product CD4 Primärantikörper
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- Applikationshinweise
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Flow Cytometry: use 10 μL of 1/100-1/200 diluted antibody to label 10^6 cells in 100 μL. Immunohistochemistry on Frozen Sections. Functional asssays.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1.0 mg/mL
- Buffer
- PBS, pH 7.4 without preservatives.
- Konservierungsmittel
- Without preservative
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
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- Target
- CD4
- Andere Bezeichnung
- CD4 (CD4 Produkte)
- Hintergrund
- CD4, a single chain transmembrane glycoprotein, is found on a T cell subset (helper/inducer) representing 45 % of peripheral blood lymphocytes. It is also present on 80 % of thymocytes and at a lower level on monocytes. It is involved in recognition of antigen presented along with MHC class II by APCs. It serves as receptor for HIV.Synonyms: T-cell surface antigen T4/Leu-3, T-cell surface glycoprotein CD4
- Gen-ID
- 12504
- NCBI Accession
- NP_038516
- UniProt
- P06332
- Pathways
- T-Zell Rezeptor Signalweg, Maintenance of Protein Location, CXCR4-mediated Signaling Events
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