CD14 Antikörper
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- Target Alle CD14 Antikörper anzeigen
- CD14
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Reaktivität
- Human, Affe, Schwein, Rind (Kuh), Schaf, Hund, Ziege, Cat, Kaninchen, Nerz
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser CD14 Antikörper ist unkonjugiert
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Applikation
- Flow Cytometry (FACS), Western Blotting (WB), Functional Studies (Func), Enzyme Immunoassay (EIA)
- Aufreinigung
- Affinity chromatography on Protein G
- Endotoxin-Niveau
- Low Endotoxin
- Klon
- Tük4
- Isotyp
- IgG2a
- Top Product
- Discover our top product CD14 Primärantikörper
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- Applikationshinweise
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Flow Cytometry: 1/100 - 1/200, use 10 μL of suggested working dilution to label 1x10^6 cells or 100 μL whole blood. ELISA. Western Blot: under reducing conditions. Functional Assays.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. Further Comments: Endotoxin Level: less than 0.01 EU/ug - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1.0 mg/mL
- Buffer
- PBS
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- -20 °C
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- Target
- CD14
- Andere Bezeichnung
- CD14 (CD14 Produkte)
- Synonyme
- CD14 molecule antikoerper, CD14 antigen antikoerper, CD14 antikoerper, Cd14 antikoerper
- Hintergrund
- CD14 is a single copy gene encoding 2 protein forms: a 50 to 55 kDa glycosylphosphatidylinositol anchored membrane protein (mCD14) and a monocyte or liver derived soluble serum protein (sCD14) that lacks the anchor. Both molecules are critical for lipopolysaccharide (LPS) dependent signal transduction, and sCD14 confers LPS sensitivity to cells lacking mCD14. Increased sCD14 levels are associated with inflammatory infectious diseases and high mortality in gram negative shock. CD14 also appears to be involved in clearance of gram-negative bacteria via its high affinity binding to LPS-LPB complexes.Synonyms: Monocyte differentiation antigen CD14, Myeloid cell-specific leucine-rich glycoprotein
- Gen-ID
- 9606
- UniProt
- P08571
- Pathways
- TLR Signalweg, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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