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CD59 Antikörper (FITC)

CD59 Reaktivität: Human FACS Wirt: Maus Monoclonal MEM-43 FITC

Produktnummer ABIN118750

Datenblatt (PDF)

Target Alle CD59 Antikörper anzeigen

CD59
Reaktivität
146

14

9

8

5

3

2

1

1
Human
Wirt
91

74

6

6
Maus
Passende Sekundärantikörper
Klonalität
100

74

1
Monoklonal
Konjugat
81

21

16

14

6

4

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1
Dieser CD59 Antikörper ist konjugiert mit FITC
Applikation
105

69

46

44

32

28

26

17

14

14

13

13

11

11

8

3

3

3

1

1

1
Flow Cytometry (FACS)

Spezifität

SM1145F reacts with well defined epitope (W40, R-53) on CD59 (Protectin), an 18-20 kDa glycosylphosphatidylinositol (GPI)-anchored glycoprotein expressed on all hematopoietic cells, it is widely present on cells in all tissues.

Immunogen

Thymocytes and T lymphocytes

Klon

MEM-43

Isotyp

IgG2a

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anti-CD59 (CD59) antibody
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CD59 Reaktivität: Human, Maus FACS, WB, IP, IHC (p) Wirt: Maus Monoclonal MEM-43-5 unconjugated

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CD59 Reaktivität: Human FACS, WB, IHC, ELISA, IF/ICC Wirt: Maus Monoclonal unconjugated

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CD59 Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal 3G6 unconjugated

anti-CD59 (CD59) (AA 26-102) antibody
CD59 Reaktivität: Human WB, IHC, ELISA, IF Wirt: Kaninchen Polyclonal unconjugated

anti-CD59 (CD59) antibody (Biotin)
CD59 Reaktivität: Human FACS, IP, IHC (p) Wirt: Maus Monoclonal MEM-43 Biotin

anti-CD59 (CD59) antibody (FITC)
CD59 Reaktivität: Human FACS Wirt: Maus Monoclonal MEM-43 FITC

Applikationshinweise

Flow cytometry analysis of human blood cells using 20 μL reagent / 100 μL of whole blood or 10^6 cells in a suspension.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen

Nur für Forschungszwecke einsetzbar
Buffer

PBS containing 15 mM Sodium Azide and 0.2 % (w/v) high-grade protease free BSA as a stabilizing agent

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung

Avoid repeated freezing and thawing.

Lagerung

4 °C/-20 °C

Informationen zur Lagerung

Store the antibody at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Should this product contain a precipitate we recommend microcentrifugation before use. This product should be stored undiluted.
Target

CD59

Andere Bezeichnung

CD59 (CD59 Produkte)

Hintergrund

CD59 (Protectin) is a small (18-20 kDa) GPI-anchored ubiquitously expressed inhibitor of the membrane attack complex (MAC). It is thus the key regulator that preserves the autologous cells from terminal effector mechanism of the complement cascade. CD59 associates with C5b-8 complex and thereby counteracts appropriate formation of cytolytic pore within the plasma membrane. CD59 is also an low-affinity ligand of human CD2 and causes T cell costimulation.Synonyms: 20 kDa homologous restriction factor, HRF-20, HRF20, MAC-IP, MAC-inhibitory protein, MACIF, MEM43 antigen, MIC11, MIN1, MIN2, MIN3, MIRL, MSK21, Membrane attack complex inhibition factor, Membrane inhibitor of reactive lysis, Protectin

Gen-ID

966

NCBI Accession

NP_000602

UniProt

P13987

Pathways

Komplementsystem