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CD59 Antikörper (PE)

CD59 Reaktivität: Human FACS Wirt: Maus Monoclonal MEM-43 PE
Produktnummer ABIN118753
  • Target Alle CD59 Antikörper anzeigen
    CD59
    Reaktivität
    • 146
    • 14
    • 9
    • 8
    • 5
    • 3
    • 2
    • 1
    • 1
    Human
    Wirt
    • 91
    • 74
    • 6
    • 6
    Maus
    Klonalität
    • 100
    • 74
    • 1
    Monoklonal
    Konjugat
    • 81
    • 21
    • 16
    • 14
    • 6
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CD59 Antikörper ist konjugiert mit PE
    Applikation
    • 105
    • 69
    • 46
    • 44
    • 32
    • 28
    • 26
    • 17
    • 14
    • 14
    • 13
    • 13
    • 11
    • 11
    • 8
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Spezifität
    This antibody reacts with a PI-linked glycoprotein, Mw 18-20 kDa found on all types of leucocytes including platelets. MEM-43 has been shown to stimulate NK activity.
    Aufreinigung
    Affinity chromatography on Protein A.
    Klon
    MEM-43
    Isotyp
    IgG2a
    Top Product
    Discover our top product CD59 Primärantikörper
  • Applikationshinweise
    Flow Cytometry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Rekonstitution
    Restore with distilled water.
    Buffer
    BS, pH 7.4 containing 0.09 % Sodium Azide as preservative and 1 % BSA as stabilizer.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    This product is photosensitive and should be protected from light
    Lagerung
    4 °C
    Informationen zur Lagerung
    Prior to and following reconstitution store the antibody at 2-8 °C. DO NOT FREEZE!
  • Target
    CD59
    Andere Bezeichnung
    CD59 (CD59 Produkte)
    Hintergrund
    CD59 is an LY6 like protein expressed in human lymphoid cells (haemapoietic and non- haemapoietic cells), regulates the action of the complement membrane attack complex on homologous cells. It is a potent inhibitor of the complement membrane attack complex action. It acts by binding to the C8 and/or C9 complements of the membrane attack complex, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. This inhibitor appears to be species-specific. CD59 is also involved in signal transduction for T-cell activation complexed to a protein tyrosine kinaseSynonyms: 20 kDa homologous restriction factor, HRF-20, HRF20, MAC-IP, MAC-inhibitory protein, MACIF, MEM43 antigen, MIC11, MIN1, MIN2, MIN3, MIRL, MSK21, Membrane attack complex inhibition factor, Membrane inhibitor of reactive lysis, Protectin
    Gen-ID
    966
    NCBI Accession
    NP_000602
    UniProt
    P13987
    Pathways
    Komplementsystem
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