HLA-ABC Antikörper

Produktnummer ABIN118900

Produktdetails anti-HLA-ABC Antikörper

Target: HLA-ABC

Reaktivität: Human, Rind (Kuh), Cat, Affe, Primate

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser HLA-ABC Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Keine Kreuzreaktivität: Ziege, Hund, Meerschweinchen, Kaninchen, Maus, Huhn, Amphibien

Kreuzreaktivität (Details): Species reactivity (tested):Human, Cynomolgus monkey, Rhesus monkey, Chimpanzee, Macaque, Bovine, Baboon, Gorilla, Shrew.

Aufreinigung: Affinity Chromatography on Protein G

Immunogen: Purified human tonsil lymphocyte membranes

Klon: W6-32

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: ELISA. Immunoprecipitation. Immunohistochemistry on frozen sections. (Does not work on paraffin sections). Flow cytometry (1:50 - 1:100): use 10 μL of diluted antibody to label 1x10^6 cells or 100 μL whole blood. This product is routinely tested in flow cytometry on human peripheral blood lymphocytes.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS, pH 7.4, 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Referenzen für anti-HLA-ABC Antikörper (ABIN118900)

Stern, Goldman, Hatasaka, Mackenzie, Surrey, Racowsky,: "Optimizing the number of cleavage stage embryos to transfer on day 3 in women 38 years of age and older: a Society for Assisted Reproductive Technology database study." in: Fertility and sterility, (2008) (PubMed).

Mayr, Kofler, Büning, Bund, Hallek, Wendtner: "Transduction of CLL cells by CD40 ligand enhances an antigen-specific immune recognition by autologous T cells." in: Blood, Vol. 106, Issue 9, pp. 3223-6, (2005) (PubMed).

Mayr, Bund, Schlee, Moosmann, Kofler, Hallek, Wendtner: "Fibromodulin as a novel tumor-associated antigen (TAA) in chronic lymphocytic leukemia (CLL), which allows expansion of specific CD8+ autologous T lymphocytes." in: Blood, Vol. 105, Issue 4, pp. 1566-73, (2005) (PubMed).

Details zu HLA-ABC

Target: HLA-ABC

Andere Bezeichnung: HLA Class I ABC (HLA-ABC Produkte)

Synonyme: HLAA antikoerper, major histocompatibility complex, class I, A antikoerper, HLA-A antikoerper

Hintergrund: The major histocompatibility complex (MHC) is a cluster of genes that are important in the immune response to infections. In humans, this complex is referred to as the human leukocyte antigen (HLA) region. There are 3 major MHC class I proteins encoded by the HLA which are HLA A, HLA B and HLA C. These proteins are found on the surface of almost all nucleated somatic cells.Synonyms: HLA Class 2 ABC, Human Leukocyte antigen class I ABC, MHC class I ABC, Major Histocompatibility complex class I

Pathways: T-Zell Rezeptor Signalweg, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints