MHC Class II HLA-DP/DQ/DR Antikörper (FITC)

Produktnummer ABIN118903

Produktdetails anti-MHC Class II HLA-DP/DQ/DR Antikörper (FITC)

Target: MHC Class II HLA-DP/DQ/DR (HLA-DP/DQ/DR)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser MHC Class II HLA-DP/DQ/DR Antikörper ist konjugiert mit FITC

Applikation: Flow Cytometry (FACS)

Aufreinigung: Affinity Chromatography on Protein G.

Immunogen: Human HLA Class II. Spleen cells from immunised BALB/c mice were fused with cells of the mouse NS.0 myeloma cell line.

Klon: WR18

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Flow Cytometry: Neat - 1/10, Use 10 μL of the suggested working dilution to label 10^6 cells or 100 μL whole blood.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.1 mg/mL

Buffer: PBS, pH 7.4 containing 0.09 % Sodium Azide as preservative and 1 % BSA as stabilzer.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing. This product is photosensitive and should be protected from light.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu MHC Class II HLA-DP/DQ/DR

Target: MHC Class II HLA-DP/DQ/DR (HLA-DP/DQ/DR)

Andere Bezeichnung: HLA Class II DP, DR, DQ (HLA-DP/DQ/DR Produkte)

Hintergrund: The major histocompatibility complex (MHC) is a large genomic region or gene family found in most vertebrates containing many genes with important immune system roles. In humans, the MHC spans almost 4 megabases of chromosome 6 and includes more than 200 known genes, of which about half have known immmunological functions. The best known genes in the MHC region are the subset that encodes cell-surface antigen-presenting proteins. In humans, these genes are referred to as human leukocyte antigen (HLA) genes. The most intensely studied HLA genes are: HLA A, HLA B, HLA C, HLA DPA, HLA DPB1, HLA DQA1, HLA DQB1, HLA DRA, and HLA DRB1. In humans, the HLA is divided into three regions: Class I, II, and III. The A, B, and C genes belong to HLA class I while the six D genes belong to class II. The antigen is expressed by B lymphocytes, monocytes and activated T lymphocytes.Synonyms: DQ, DR, HLA class II histocompatibility antigen DP, MHC class II antigen DP

Pathways: Human Leukocyte Antigen (HLA) in Adaptive Immune Response