TLR4 Antikörper (PE)
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- Target Alle TLR4 Antikörper anzeigen
- TLR4 (Toll-Like Receptor 4 (TLR4))
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Reaktivität
- Human, Hund, Schwein, Meerschweinchen, Affe
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser TLR4 Antikörper ist konjugiert mit PE
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Applikation
- Flow Cytometry (FACS)
- Kreuzreaktivität (Details)
- Species reactivity (tested):Human, Rhesus Monkey, Guinea Pig, Porcine and Canine (Dog).
- Aufreinigung
- Affinity Chromatography on Protein G
- Immunogen
- Ba/F3 cell line expressing TLR4 (CD284). Spleen cells from immunised Balb/c mice were fused with cells of the mouse SP2/0 myeloma cell line.
- Klon
- HTA125
- Isotyp
- IgG2a
- Top Product
- Discover our top product TLR4 Primärantikörper
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- Applikationshinweise
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Flow Cytometry: use 10 μL of neat antibody to label 10^6 cells or 100 μL whole blood.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Rekonstitution
- Restore with 1.0 mL distilled water.
- Buffer
- PBS, 0.09 % Sodium Azide, 1 % BSA and 5 % Sucrose
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Prior to and following reconstitution store the antibody at -20 °C.
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- Target
- TLR4 (Toll-Like Receptor 4 (TLR4))
- Andere Bezeichnung
- CD284 / TLR4 (TLR4 Produkte)
- Hintergrund
- TLR4, also known as CD284, has been demonstrated to act as a receptor for LPS on human monocytes and macrophages. TLR4 signalling of LPS stimulation requires the presence of the MD-2 Molecule. TLR4 is weakly expressed by resting cells, but is upregulated following stimulation with LPS.Synonyms: Toll-like receptor 4
- NCBI Accession
- NM_138554
- UniProt
- O00206
- Pathways
- TLR Signalweg, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades, Inflammasome, S100 Proteine
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