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CD80 Antikörper

CD80 Reaktivität: Human FACS, WB, IP Wirt: Maus Monoclonal MEM-233 unconjugated

Produktnummer ABIN119430

Datenblatt (PDF)

Target Alle CD80 Antikörper anzeigen

CD80
Reaktivität
148

114

46

7

6

6

1

1

1
Human
Wirt
92

80

22

21

21

2

1
Maus
Passende Sekundärantikörper
Klonalität
157

79

2
Monoklonal
Konjugat
95

20

20

17

13

5

4

4

4

4

3

3

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1
Dieser CD80 Antikörper ist unkonjugiert
Applikation
141

93

68

39

38

25

14

13

13

13

11

10

10

6

5

4

3

3

2

2

2

1

1

1

1

1

1

1
Flow Cytometry (FACS), Western Blotting (WB), Immunoprecipitation (IP)

Spezifität

This antibody recognises the CD80 cell surface antigen, also known as B7-1.

Aufreinigung

Affinity chromatography on Protein A

Klon

MEM-233

Isotyp

IgG1

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anti-CD80 (CD80) (AA 35-288) antibody
CD80 Reaktivität: Human FACS, ELISA, IHC Wirt: Maus Monoclonal 1G3D7 unconjugated

anti-CD80 (CD80) antibody
CD80 Reaktivität: Maus, Hund FACS, IP, IHC (fro) Wirt: Armenischer Hamster Monoclonal 16-10A1 unconjugated

anti-CD80 (CD80) (Extracellular Domain) antibody
CD80 Reaktivität: Human FACS, IP Wirt: Maus Monoclonal MEM-233 unconjugated

anti-CD80 (CD80) (AA 38-246) antibody
CD80 Reaktivität: Maus WB, IP, IHC, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-CD80 (CD80) (Extracellular Domain) antibody (FITC)
CD80 Reaktivität: Human FACS Wirt: Maus Monoclonal MEM-233 FITC

anti-CD80 (CD80) (AA 251-321) antibody
CD80 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC (p), ICC, IHC (fro), IF (cc), IF (p) Wirt: Kaninchen Polyclonal unconjugated

anti-CD80 (CD80) (Extracellular Domain) antibody (PerCP)
CD80 Reaktivität: Human FACS Wirt: Maus Monoclonal MEM-233 PerCP

anti-CD80 (CD80) (Extracellular Domain) antibody (APC)
CD80 Reaktivität: Human FACS Wirt: Maus Monoclonal MEM-233 APC

anti-CD80 (CD80) (Extracellular Domain) antibody (PE)
CD80 Reaktivität: Human FACS Wirt: Maus Monoclonal MEM-233 PE

anti-CD80 (CD80) antibody
CD80 Reaktivität: Human ELISA, IHC, ICC Wirt: Maus Monoclonal 2A2 unconjugated

Applikationshinweise

Flow Cytometry. Immunoprecipitation. Western Blot.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen

Nur für Forschungszwecke einsetzbar
Konzentration

1.0 mg/mL

Buffer

PBS

Konservierungsmittel

Azide free

Handhabung

Avoid repeated freezing and thawing.

Lagerung

-20 °C
Target

CD80

Andere Bezeichnung

CD80 (CD80 Produkte)

Hintergrund

CD80 is a member of the Ig superfamily and serves as the ligand for two T cell molecules, CD28 and CTLA4. Interactions between CD28 and CD80 on activated B cells result in enhanced T cell activation. CD80 is rapidly induced on the surface of in vitro activated B cells, Epstein Barr Virus (EBV) transformed B cell lines, Burkitts lymphoma cell lines, freshly isolated follicular B lymphoma cells, T cells, and monocytes. It is also expressed at high levels in dendritic cells. It reacts weakly with a small proportion of non activated normal B cells and with HTLV1 infected T cells. CD80 does not react with peripheral monocytes, resting and activated normal T cells, T cell lines and T cell clones, nor with myelomonocytic cell lines. CD80 is expressed by activated B cells, and is important in B cell - T cell interactions, being a ligand of CD28 and CD152 (CTLA-4).Synonyms: Activation B7-1 antigen, B7-1, B7.1, BB1, CD28LG, CD28LG1, CTLA-4 counter-receptor B7.1, LAB7, T-lymphocyte activation antigen CD80

Gen-ID

941

NCBI Accession

NP_005182

UniProt

P33681

Pathways

T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints