CD226 Antikörper
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- Target Alle CD226 Antikörper anzeigen
- CD226
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser CD226 Antikörper ist unkonjugiert
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Applikation
- Flow Cytometry (FACS), Immunoprecipitation (IP), Functional Studies (Func)
- Spezifität
- This antibody recognises CD226. Clone DX11 is reported to inhibit T- and NK cell mediated cytotoxicity against tumour cell targets and to block TNF alpha and IFN gamma secretion by alloantigen-specific T-cells
- Aufreinigung
- Affinity chromatography on Protein G
- Endotoxin-Niveau
- Low Endotoxin
- Immunogen
- Human cytotoxic T lymphocyte clone. Spleen cells from immunised BALB/c mouse were fused with cells of the Sp2/0 myeloma cell line.
- Klon
- DX11
- Isotyp
- IgG1
- Top Product
- Discover our top product CD226 Primärantikörper
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- Applikationshinweise
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Flow Cytometry: 1/50 - 1/200, Use 10 μL of the suggested working dilution to label 1 x 10^6 cells in 100 μL. Immunoprecipitation. Functional Assays.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. Further Comments: Endotoxin Level: less than 0.01 EU/ug - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1.0 mg/mL
- Buffer
- PBS, pH 7.4
- Handhabung
- Avoid repeated freezing and thawing. Should this product contain a precipitate, we recommend centrifugation before use.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store the antibody at -20 °C. Can be shipped at 2 - 8 °C.
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- Target
- CD226
- Andere Bezeichnung
- CD226 / DNAM1 (CD226 Produkte)
- Hintergrund
- CD226 is a 65kD glycoprotein, also known as DNAM1 (DNAX accessory molecule-1). CD226 is broadly expressed on T-cells, NK cells, platelets, monocytes and a subset of B cells. CD226 is also expressed by a subset of CD3 positive thymocytes.Synonyms: DNAM-1, DNAX accessory molecule 1
- Gen-ID
- 10666
- NCBI Accession
- NP_006557
- UniProt
- Q15762
- Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
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