This antibody recognises CD102, also known as intercellular adhesion molecule-2 (ICAM-2). Clone CBR-IC2/2 is reported to inhibit interactions between CD102 and LFA-1. We recommend the use of SM2223LE for this purpose.
Aufreinigung
Affinity chromatography on Protein G
Immunogen
Transfected COS cells expressing ICAM-2 cDNA. Cells from immunised BALB/c mice were fused with cells of the Murine P3X63Ag.653 myeloma cell line.
ICAM2
Reaktivität: Human
WB
Wirt: Maus
Polyclonal
unconjugated
Applikationshinweise
Flow Cytometry: 1/100, Use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL. Immunoprecipitation. Immunohistochemistry on frozen sections. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Konzentration
1.0 mg/mL
Buffer
PBS, pH 7.4 containing 0.09 % Sodium Azide
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Avoid repeated freezing and thawing.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
CD102 is a glycosylated cell surface protein that is broadly expressed on most leucocytes and is strongly expressed by endothelial cells. CD102 interacts with the CD11a/CD18 (LFA-1). Reports suggest that the CD102 may play a role in lymphocyte re-circulation and T-cell activation.Synonyms: ICAM-2, Intercellular adhesion molecule 2