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CD14 Antikörper

CD14 Reaktivität: Human, Primate FACS, IP Wirt: Maus Monoclonal MEM-15 unconjugated
Produktnummer ABIN120779
  • Target Alle CD14 Antikörper anzeigen
    CD14
    Reaktivität
    • 253
    • 45
    • 40
    • 27
    • 24
    • 23
    • 23
    • 23
    • 20
    • 17
    • 16
    • 15
    • 14
    • 14
    • 13
    • 10
    • 7
    • 7
    • 6
    • 5
    • 5
    • 2
    • 1
    • 1
    Human, Primate
    Wirt
    • 225
    • 53
    • 25
    • 3
    • 1
    Maus
    Klonalität
    • 252
    • 54
    • 1
    Monoklonal
    Konjugat
    • 125
    • 33
    • 25
    • 20
    • 15
    • 8
    • 6
    • 5
    • 5
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CD14 Antikörper ist unkonjugiert
    Applikation
    • 231
    • 89
    • 65
    • 57
    • 54
    • 52
    • 22
    • 16
    • 13
    • 12
    • 7
    • 6
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Immunoprecipitation (IP)
    Kreuzreaktivität (Details)
    Species reactivity (tested):Human, non-Human Primates
    Aufreinigung
    Protein A affinity chromatography
    Reinheit
    > 95 % (by SDS-PAGE)
    Immunogen
    A crude mixture of human urinary proteins precipitated by ammonium sulphate from the urine of a patient suffering from proteinuria
    Klon
    MEM-15
    Isotyp
    IgG1
    Top Product
    Discover our top product CD14 Primärantikörper
  • Applikationshinweise
    Flow cytometry. Immunoprecipitation.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1.0 mg/mL
    Buffer
    Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
    Shelf Life: one year from despatch.
    Haltbarkeit
    12 months
  • Target
    CD14
    Andere Bezeichnung
    CD14 (CD14 Produkte)
    Hintergrund
    CD14 is a 55 kDa GPI-anchored glycoprotein, constitutively expressed on the surface of mature monocytes, macrophages, and neutrophils, where serves as a multifunctional lipopolysaccharide receptor, it is also released to the serum both as a secreted and enzymatically cleaved GPI-anchored form. CD14 binds lipopolysaccharide molecule in a reaction catalyzed by lipopolysaccharide-binding protein (LBP), an acute phase serum protein. The soluble sCD14 is able to discriminate slight structural differences between lipopolysaccharides and is important for neutralization of serum allochthonous lipopolysaccharides by reconstituted lipoprotein particles. CD14 affects allergic, inflammatory and infectious processes.Synonyms: Monocyte differentiation antigen CD14, Myeloid cell-specific leucine-rich glycoprotein
    UniProt
    P08571
    Pathways
    TLR Signalweg, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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