NCR1 Antikörper

Produktnummer ABIN121147

Produktdetails anti-NCR1 Antikörper

Target: NCR1 (Natural Cytotoxicity Triggering Receptor 1 (NCR1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser NCR1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)

Spezifität: This antibody is specific for NKp46.

Aufreinigung: Protein-G affinity chromatography

Immunogen: Recombinant human NKp46 protein

Klon: N1D9

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Flow cytometry. ELISA. Western blot.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. Further Comments: This product is routinely tested on peripheral blood mononuclear cells (PBMCs) or natural killer(NK) cells. The histogram is an example of the flow cytometric analyses.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.0 mg/mL

Buffer: PBS, pH 7.4 containing 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf Life: one year from despatch.

Haltbarkeit: 12 months

Details zu NCR1

Target: NCR1 (Natural Cytotoxicity Triggering Receptor 1 (NCR1))

Andere Bezeichnung: CD335 / NKp46 (NCR1 Produkte)

Synonyme: CD335 antikoerper, LY94 antikoerper, NK-p46 antikoerper, NKP46 antikoerper, Ly94 antikoerper, NKp46 antikoerper, KILR-1 antikoerper, Nk-p46 antikoerper, Nkp46 antikoerper, natural cytotoxicity triggering receptor 1 antikoerper, NCR1 antikoerper, Ncr1 antikoerper

Hintergrund: A natural cytotoxicity receptor (NCR), NKp46, is a glycoprotein that has two extracellular Ig-like domains followed by a ~40 residue stalk resion, a type I transmembrane domain, and a short cytoplasmic tail. NKp46 has been shown to represent a novel NK cell-specific molecule involved in human NK cell activation. The natural cytotoxicity receptors (NCRs) are a recently characterized family of Ig-like activation receptors that appear to be major triggering receptors in tumor cell recognition. NKp46 has been implicated in NK cell-mediated lysis of several autologous tumor cells and pathogen-infected cell lines.Synonyms: LY94, NCR1, NK cell-activating receptor, NKp46, Natural cytotoxicity triggering receptor, Natural killer cell p46-related protei

UniProt: O76036

Pathways: Regulation of Leukocyte Mediated Immunity